2-Chloro-4-(4-methoxyphenoxy)benzaldehyde CAS 1092294-34-2
| CAS No. | 1092294-34-2 |
| Molecular Formula | C14H11ClO3 |
| Molecular Weight | 262.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-4-(4-methoxyphenoxy)benzaldehyde (CAS 1092294-34-2), molecular formula C14H11ClO3 and molecular weight 262.69 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Chloro-4-(4-methoxyphenoxy)benzaldehyde (C14H11ClO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Chloro-4-(4-methoxyphenoxy)benzaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H11ClO3 |
| Molecular Weight | 262.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
Related Chloro Standards
- 3-Chloro-4-hydroxy-N-(5-methylpyridin-2-yl)benzamide (CAS 1017109-71-5)
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- 2-Chloro-N-(2-methoxyphenyl)isonicotinamide (CAS 1019384-16-7)
- 3-Chloro-4-hydroxy-n-(pyridin-3-ylmethyl)benzamide (CAS 1041525-50-1)
- 3-chloro-4-hydroxy-N-(pyridin-4-ylmethyl)benzamide (CAS 1041593-73-0)
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Recommended Standards
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- 4-(Benzyloxy)-5-chloro-2-hydroxybenzaldehyde (CAS 1043920-04-2)
- 3,3’,5-Triiodo-L-thyronine-13C6 (CAS 1217843-81-6)
- 4-(3-Isopropyl-1-methyl-1h-1,2,4-triazol-5-yl)thiazol-2-amine (CAS 1342674-62-7)
- 2-Chloro-1-{4-phenyl-4h,5h,6h,7h-thieno[3,2-c]pyridin-5-yl}ethan-1-one (CAS 1311313-65-1)
- 5-Fluoro-2-methoxy-N-(2-morpholinoethyl)benzenesulfonamide (CAS 878655-56-2)
- 3-(((1,5-Dimethyl-1h-pyrazol-4-yl)methyl)amino)propan-1-ol (CAS 1530811-03-0)
- 4-(3-Fluorophenoxy)-2-(trifluoromethyl)aniline (CAS 946663-14-5)
- 4-cyclobutoxypyridine-2-carbonitrile (CAS 1344306-63-3)
- Methylbis[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl]amine (CAS 2377609-51-1)
- 3-Methylhistidine methyl ester (CAS 1207948-24-0)
- Cyclolinopeptide B (CAS 193139-41-2)
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