N-(4-Chlorophenyl)-4,6-bis(trifluoromethyl)pyridine-2-carboxamide CAS 1092345-03-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1092345-03-3
Molecular FormulaC14H7ClF6N2O
Molecular Weight368.66 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(4-Chlorophenyl)-4,6-bis(trifluoromethyl)pyridine-2-carboxamide CAS 1092345-03-3 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(4-Chlorophenyl)-4,6-bis(trifluoromethyl)pyridine-2-carboxamide.

N-(4-Chlorophenyl)-4,6-bis(trifluoromethyl)pyridine-2-carboxamide (CAS 1092345-03-3) is a high-purity analytical reference standard with the molecular formula C14H7ClF6N2O and a molecular weight of 368.66 g/mol.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, N-(4-Chlorophenyl)-4,6-bis(trifluoromethyl)pyridine-2-carboxamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 368.66 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), N-(4-Chlorophenyl)-4,6-bis(trifluoromethyl)pyridine-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC14H7ClF6N2O
Molecular Weight368.66 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentF/Cl-containing
Nitrogen Atoms2

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