1-[4,6-Bis(trifluoromethyl)pyridine-2-carbonyl]-4-[3-(trifluoromethyl)phenyl]piperazine CAS 1092345-33-9
| CAS No. | 1092345-33-9 |
| Molecular Formula | C19H14F9N3O |
| Molecular Weight | 471.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-[4,6-Bis(trifluoromethyl)pyridine-2-carbonyl]-4-[3-(trifluoromethyl)phenyl]piperazine (C19H14F9N3O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 1-[4,6-Bis(trifluoromethyl)pyridine-2-carbonyl]-4-[3-(trifluoromethyl)phenyl]piperazine (CAS 1092345-33-9), a certified reference material (molecular formula C19H14F9N3O, MW 471.32 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-[4,6-Bis(trifluoromethyl)pyridine-2-carbonyl]-4-[3-(trifluoromethyl)phenyl]piperazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H14F9N3O |
| Molecular Weight | 471.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Bis Standards
- 1-(4-{[2-oxo-5-(trifluoromethyl)-1,2-dihydropyridin-1-yl]methyl}phenyl)-3-[4-(trifluoromethoxy)phenyl]urea (CAS 339025-59-1)
- 3-(Trifluoromethyl)-N-(4-(((3-(trifluoromethyl)phenyl)sulfinyl)methyl)phenyl)benzamide (CAS 477710-63-7)
- 3-[3,5-bis(trifluoromethyl)phenyl]-N'-({[(1,2,2-trichlorovinyl)amino]carbonyl}oxy)prop-2-enimidamide (CAS 646989-54-0)
- 3-{benzyl[3-(trifluoromethyl)phenyl]sulfamoyl}-4-chlorobenzoic acid (CAS 721418-23-1)
- 5-{benzyl[3-(trifluoromethyl)phenyl]sulfamoyl}-2-chlorobenzoic acid (CAS 722464-39-3)
- N-(3-(3-(trifluoromethyl)phenoxy)benzyl)-N-(2,2,4-trimethyl-2,3-dihydrobenzofuran-7-yl)acetamide (CAS 866042-53-7)
- 3-(Trifluoromethyl)-N-{4-[3-(trifluoromethyl)benzenesulfonyl]phenyl}benzamide (CAS 339104-90-4)
- Ethyl 3-[3-(trifluoromethyl)phenyl]-5-{[3-(trifluoromethyl)phenyl]sulfanyl}-1,2,4-triazine-6-carboxylate (CAS 338956-94-8)
Recommended Standards
- 5-(3,4-Dichlorophenyl)-4-(3-fluoro-4-methylbenzoyl)-3-hydroxy-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one (CAS 618076-11-2)
- (S)-Methyl 2-amino-3-(3,5-dichloro-4-((2-phenyl-benzo[d]oxazol-7-yl)methoxy)phenyl)propanoate (CAS 728862-92-8)
- (5-(4-Fluorophenoxy)-1-methyl-3-phenyl-1H-pyrazol-4-yl)methyl 2,4-dichlorobenzoate (CAS 318289-18-8)
- Alendronic Acid Impurity 4 (CAS 2763925-95-5)
- (2-Methylquinolin-4-yl)(piperazin-1-yl)methanone (CAS 63591-79-7)
- N-ethyl-2-(methylthio)-6-morpholinopyrimidin-4-amine (CAS 478258-66-1)
- 1-(5-Bromo-2-fluorobenzyl)-4-ethylpiperazine (CAS 1318910-45-0)
- 4-Chloro-1,5-dimethyl-1H-pyrazole-3-carbaldehyde (CAS 1306610-19-4)
- 2-(Pyridin-4-yl)pyrimidine-5-carbaldehyde (CAS 954227-09-9)
- (S)-N-(2-Benzoyl-4-chlorophenyl)-2-(3,5-dihydro-4H-dinaphtho[2,1-c:1',2'-e]azepin-4-yl)acetamide (CAS 1614264-49-1)
- 1-Benzyl-4-piperidin-4-yl-piperazine 1h-pyrrolo[2,3-b]pyridine, 5-iodo- 5-iodo-1h-pyrrolo[2,3-b]pyridine 5-iodo-7-azaindole 898746-50-4 (CAS 898746-50-4)
- Ethyl 2-(pyridazin-4-yl)thiazole-4-carboxylate (CAS 955399-62-9)
- 2-Cyano-2-(pyrazin-2-yl)acetamide (CAS 129794-39-4)
- Tirzepatide Impurity 10 (CAS CATO-C4X-324010)
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