5,8-Difluoro-7-methoxy-3,4-dihydronaphthalen-1(2H)-one CAS 1092347-75-5
| CAS No. | 1092347-75-5 |
| Molecular Formula | C11H10F2O2 |
| Molecular Weight | 212.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 5,8-Difluoro-7-methoxy-3,4-dihydronaphthalen-1(2H)-one (CAS 1092347-75-5), a certified reference material (molecular formula C11H10F2O2, MW 212.19 g/mol) for analytical method development and quality control.
The molecular framework of 5,8-Difluoro-7-methoxy-3,4-dihydronaphthalen-1(2H)-one (C11H10F2O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H10F2O2 |
| Molecular Weight | 212.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
Related Difluoro Standards
- 2,2-Difluoro-cyclopropanecarboxylic acid benzyl ester (CAS 1393576-46-9)
- 4,4-difluoro-1-(p-tolyl)butane-1,3-dione (CAS 165328-11-0)
- 2,2-Difluoro-1-(p-tolyl)cyclopropane-1-carboxylic acid (CAS 1707737-35-6)
- 2,2-Difluoro-1-(m-tolyl)cyclopropane-1-carboxylic acid (CAS 1710345-30-4)
- 2,2-Difluoro-1-(o-tolyl)cyclopropane-1-carboxylic acid (CAS 1774902-99-6)
- 2,2-Difluoro-3-Hydroxy-1-Phenyl-4-Penten-1-One (CAS 209474-41-9)
- 2-(5,7-Difluoro-1H-benzo[d]imidazol-2-yl)propan-2-ol (CAS 1499989-25-1)
- 2,2-Difluoro-2-(4-hydroxytetrahydro-2h-thiopyran-4-yl)acetic acid (CAS 681240-13-1)
Recommended Standards
- 1-(2,6-Difluorophenyl)pentane-1,3-dione (CAS 1040075-32-8)
- 7-(Difluoromethoxy)-3,4-dihydronaphthalen-1(2H)-one (CAS 1092348-41-8)
- (2-(2,2,2-Trifluoroethoxy)thiazol-5-yl)methanamine (CAS 1003853-96-0)
- 3,3-Difluorocyclobutyl benzoate (CAS 1215071-19-4)
- 1,7,8-Trichloroisoquinoline (CAS 1378261-18-7)
- N,N'-(ethane-1,2-diyl)bis(2-chloro-N-(4-methylbenzyl)benzamide) (CAS 338775-55-6)
- (5-(Trifluoromethyl)pyrazin-2-yl)methanol (CAS 2168049-57-6)
- Bendamustine USP Related Compound D (CAS 1797881-48-1)
- 4-Isopropylnicotinimidamide (CAS 1256809-58-1)
- 1-(5-(Chloromethyl)-1,3,4-thiadiazol-2-yl)-2-methyl-4-((2-phenyl-1H-indol-3-yl)methylene)-1H-imidazol-5(4H)-one (CAS 143658-86-0)
- N-(4-Ethynylphenyl)cyclopropanecarboxamide (CAS 1842341-45-0)
- 2-(Difluoromethyl)-3-nitro-6-(trifluoromethoxy)pyridine-4-carboxylic acid (CAS 1805226-01-0)
- 6-Methoxy-4-nitro-1H-indole (CAS 885520-66-1)
- Semaglutide Impurity 131 (CAS 2618647-80-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com