Tert-butyl 4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)piperidine-1-carboxylate CAS 1092352-86-7
| CAS No. | 1092352-86-7 |
| Molecular Formula | C16H21ClF3N3O2 |
| Molecular Weight | 379.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Tert-butyl 4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)piperidine-1-carboxylate (CAS 1092352-86-7), molecular formula C16H21ClF3N3O2 and molecular weight 379.81 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, Tert-butyl 4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)piperidine-1-carboxylate (C16H21ClF3N3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 379.81 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Tert-butyl 4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)piperidine-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H21ClF3N3O2 |
| Molecular Weight | 379.81 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Recommended Standards
- 10-Chlorobenzo[e]benzo[4,5]imidazo[1,2-c][1,2,3]triazine (CAS 10211-11-7)
- Tert-butyl 4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)piperazine-1-carboxylate (CAS 1311278-11-1)
- 8-Chloro-1-cyclopropyl-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 101987-76-2)
- Tert-butyl (1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperidin-3-yl)carbamate (CAS 1333866-93-5)
- (S)-2-[Bis(3,5-dimethylphenyl)[(trimethylsilyl)oxy]methyl]pyrrolidine (CAS 848821-60-3)
- 3-Methoxy-2-(trifluoromethyl)benzoic acid (CAS 1214384-93-6)
- 5-(4-((2,4-Dichlorophenyl)sulfonyl)piperazin-1-yl)-6-phenylpyridazin-3(2H)-one (CAS 477863-54-0)
- Peramivir impurity 111 (CAS 2641684-79-7)
- Tert-butyl 2-amino-4-methyl-6,7-dihydrothiazolo[4,5-c]pyridine-5(4H)-carboxylate (CAS 2180093-91-6)
- 5-Ethylindole-3-carbaldehyde (CAS 68742-29-0)
- tert-Butyl 2-(but-3-yn-1-yloxy)acetate (CAS 157992-79-5)
- 2-Acetamido-4h,5h,6h-cyclopenta[b]thiophene-3-carboxylic acid (CAS 80414-37-5)
- 2-Chloro-5-methoxy-1H-indole (CAS 119730-01-7)
- Serpent Peptide (CAS 823202-99-9)
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