Ethyl 4-bromonicotinate CAS 1092353-02-0
| CAS No. | 1092353-02-0 |
| Molecular Formula | C8H8BrNO2 |
| Molecular Weight | 230.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies Ethyl 4-bromonicotinate (CAS 1092353-02-0), a certified reference material (molecular formula C8H8BrNO2, MW 230.06 g/mol) for analytical method development and quality control.
Ethyl 4-bromonicotinate (C8H8BrNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H8BrNO2 |
| Molecular Weight | 230.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- Ethyl 2-bromonicotinate, 97% (CAS 53087-78-8)
- Methyl 6-bromonicotinate 6-bromonicotinic acid methyl ester methyl 6-bromo-nicotinate 6-bromo-nicotinic acid methyl ester 2-bromo-5-nicotinic acid methyl ester Methyl 6-bromopyridine-3-carboxylate 6-Bromo-pyridine-3-carboxylic acid methyl ester Methyl 2-bromopyridine-5-carboxylate 26218-78-0 (CAS 26218-78-0)
- Methyl 4-bromonicotinate (CAS 1043419-29-9)
- Methyl 2-bromonicotinate (CAS 52718-95-3)
- Ethyl 5-bromonicotinate 1-oxide (CAS 279248-42-9)
- Ethyl 4-bromonicotinate hydrobromide (CAS 2586126-96-5)
Recommended Standards
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- 2-Amino-5-bromo-4-methylbenzoic acid (CAS 106976-24-3)
- Diethyl 5-bromopyridine-2,3-dicarboxylate (CAS 110239-01-5)
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- 1-Bromo-11,12-dihydroindolo[2,3-a]carbazole (CAS 2044705-99-7)
- (4-Aminophenyl)-pyrrolidin-1-ylmethanone (CAS 56302-41-1)
- 3-Hydroxy-5-phenylpyridine (CAS 31676-55-8)
- 2-(4-methylphenyl)cyclopentan-1-one (CAS 22460-07-7)
- 2-((6-Chloropyrimidin-4-yl)amino)-2-phenylethan-1-ol (CAS 1498070-12-4)
- 7-Bromo-4-(trifluoromethyl)quinolin-2-ol (CAS 847900-73-6)
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