Diethyl (1,1-difluoro-2-hydroxy-2,2-diphenylethyl)phosphonate CAS 1093490-31-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1093490-31-3
Molecular FormulaC18H21F2O4P
Molecular Weight370.33 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Diethyl (1,1-difluoro-2-hydroxy-2,2-diphenylethyl)phosphonate CAS 1093490-31-3 chemical structure

Description

The occurrence of Diethyl (1,1-difluoro-2-hydroxy-2,2-diphenylethyl)phosphonate is closely related to a flavonoid core, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

Diethyl (1,1-difluoro-2-hydroxy-2,2-diphenylethyl)phosphonate (CAS 1093490-31-3) is a high-purity analytical reference standard with the molecular formula C18H21F2O4P and a molecular weight of 370.33 g/mol.

The molecular framework of Diethyl (1,1-difluoro-2-hydroxy-2,2-diphenylethyl)phosphonate (C18H21F2O4P) is characterized by a flavonoid core, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures Diethyl (1,1-difluoro-2-hydroxy-2,2-diphenylethyl)phosphonate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC18H21F2O4P
Molecular Weight370.33 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentF-containing

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