Fmoc-His(1-Trt)-OH CAS 109425-51-6

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Fmoc-His(1-Trt)-OH.

CATO supplies Fmoc-His(1-Trt)-OH (CAS 109425-51-6), a certified reference material (molecular formula C40H33N3O4, MW 619.71 g/mol) for analytical method development and quality control.

The molecular framework of Fmoc-His(1-Trt)-OH (C40H33N3O4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), Fmoc-His(1-Trt)-OH meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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