1-[5-(4-chloro-2-fluorophenyl)thiophen-2-yl]ethan-1-one CAS 1094282-07-1
| CAS No. | 1094282-07-1 |
| Molecular Formula | C12H8ClFOS |
| Molecular Weight | 254.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-[5-(4-chloro-2-fluorophenyl)thiophen-2-yl]ethan-1-one (CAS 1094282-07-1), molecular formula C12H8ClFOS and molecular weight 254.71 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 1-[5-(4-chloro-2-fluorophenyl)thiophen-2-yl]ethan-1-one is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 254.71 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H8ClFOS |
| Molecular Weight | 254.71 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
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- 1-(3-pyridinylcarbonyl)-4-piperidinone (CAS 502925-00-0)
- 3-({1,3-dibenzyl-2-oxo-1h,2h,3h-imidazo[4,5-b]pyridin-5-yl}carbamoyl)propanoic acid (CAS 893725-89-8)
- Ginsenoside Rh1 (CAS 63223-86-9)
- 3-Phenyl-N-(2-((4-phenylpiperazin-1-yl)sulfonyl)ethyl)propanamide (CAS 897621-85-1)
- Stresscopin-Related Peptide (human) (CAS 348626-74-4)
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