2,6-Dichloro-N-(5-methylpyridin-2-yl)isonicotinamide CAS 1094554-23-0

Purity 97%+In StockPharmaceutical Standards
CAS No.1094554-23-0
Molecular FormulaC12H9Cl2N3O
Molecular Weight282.13 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2,6-Dichloro-N-(5-methylpyridin-2-yl)isonicotinamide CAS 1094554-23-0 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 282.13 g/mol gives 2,6-Dichloro-N-(5-methylpyridin-2-yl)isonicotinamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2,6-Dichloro-N-(5-methylpyridin-2-yl)isonicotinamide (CAS 1094554-23-0), molecular formula C12H9Cl2N3O and molecular weight 282.13 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2,6-Dichloro-N-(5-methylpyridin-2-yl)isonicotinamide (C12H9Cl2N3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2,6-Dichloro-N-(5-methylpyridin-2-yl)isonicotinamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H9Cl2N3O
Molecular Weight282.13 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentCl-containing
Nitrogen Atoms3

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