Sildenafil EP Impurity B CAS 1094598-75-0
| CAS No. | 1094598-75-0 |
| Molecular Formula | C22H30N6O5S |
| Molecular Weight | 490.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 490.58 g/mol gives Sildenafil EP Impurity B distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Sildenafil EP Impurity B (CAS 1094598-75-0) is a certified pharmaceutical impurity reference standard with the molecular formula C22H30N6O5S and a molecular weight of 490.58 g/mol.
Sildenafil EP Impurity B (C22H30N6O5S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Sildenafil EP Impurity B under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H30N6O5S |
| Molecular Weight | 490.58 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
Related Sildenafil Standards
- Sildenafil Impurity 84 (CAS CATO-C4X-112884)
- Sildenafil EP Impurity A (CAS 1391053-95-4)
- Sildenafil Impurity 23 (CAS 200575-15-1)
- Sildenafil Impurity 279 (CAS CATO-C4X-1128279)
- Sildenafil Impurity 301 (CAS CATO-C4X-1128301)
- Sildenafil Impurity 42 (CAS 2146091-79-2)
- Sildenafil Impurity 88 (CAS CATO-C4X-112888)
- Sildenafil-D3 (CAS 1126745-90-1)
Recommended Standards
- CAS 2761158-33-0 (CAS 2761158-33-0)
- 2,6-Bis(6-methoxynaphthalen-2-yl)anthracene (CAS 1065644-45-2)
- N-(2,6-dimethylphenyl)-2-((4-ethyl-5-(((6-oxo-1-phenyl-1,6-dihydropyridazin-3-yl)oxy)methyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 692737-11-4)
- 2,2'-((((9H-fluorene-9,9-diyl)bis(2-methyl-4,1-phenylene))bis(oxy))bis(methylene))bis(oxirane) (CAS 114205-89-9)
- Vonoprazan Impurity 72 (CAS 2416241-96-6)
- Phenylephrine Hydrochloride EP Impurity C (CAS 52093-42-2(free base))
- Pazufloxacin Impurity 16 (CAS CATO-C4X-233216)
- 16,19-Dimethoxy-3-[(2-methylphenyl)methyl]-3,21-diazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa-1(21),2(10),4(9),5,7,13,15(20),16,18-nonaene (CAS 860787-15-1)
- Vilanterol Impurity 74 (CAS CATO-C4X-193574)
- 2,2-Dimethyl-5-oxotetrahydrofuran-3-carboxylic acid (CAS 79-91-4)
- methyl 5-fluoro-6-methyl-pyrimidine-4-carboxylate (CAS 916213-46-2)
- 1-(1-Methyl-1H-1,2,3-triazol-5-yl)ethanone (CAS 194209-18-2)
- Teneligliptin Impurity 10 (CAS CATO-C4X-176010)
- Semaglutide impurity 88 (CAS CATO-C4X-222688)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com