(4-Methyl-2-(4-(trifluoromethyl)phenyl)oxazol-5-yl)methanol CAS 109544-12-9
| CAS No. | 109544-12-9 |
| Molecular Formula | C12H10F3NO2 |
| Molecular Weight | 257.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (4-Methyl-2-(4-(trifluoromethyl)phenyl)oxazol-5-yl)methanol.
CATO supplies (4-Methyl-2-(4-(trifluoromethyl)phenyl)oxazol-5-yl)methanol (CAS 109544-12-9), a certified reference material (molecular formula C12H10F3NO2, MW 257.21 g/mol) for analytical method development and quality control.
The molecular framework of (4-Methyl-2-(4-(trifluoromethyl)phenyl)oxazol-5-yl)methanol (C12H10F3NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H10F3NO2 |
| Molecular Weight | 257.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
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Recommended Standards
- Methyl 2-{[(tert-butoxy)carbonyl]amino}-3,3,3-trifluoropropanoate (CAS 1039356-94-9)
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- 1-Methyl-3-(4-(trifluoromethoxy)phenyl)-1H-pyrazol-5-amine (CAS 1019011-55-2)
- (5-(4-(Trifluoromethoxy)phenyl)-1H-imidazol-2-yl)methanamine (CAS 1156707-86-6)
- 3-{trimethyl-[1,2]oxazolo[5,4-b]pyridin-5-yl}propanoic acid (CAS 953751-49-0)
- Cobalt, dicarbonyl(dicyclohexylphosphinothioito-P,S)(tricyclohexylphosphine)-, (TB-5-23)- (CAS 112792-48-0)
- 1-(2-Fluoro-3-nitrophenyl)ethanol (CAS 1817679-73-4)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (5-(2-methoxyphenyl)thiazol-4-yl)boronate (CAS 2223030-58-6)
- 4-Cyclopropyl-1-ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 2446483-85-6)
- 4-Chloro-8-fluoro-5H-pyrimido[5,4-b]indole (CAS 331443-96-0)
- Methyl 1-(4-Chlorobenzyl)-3-phenyl-1H-pyrazole-5-carboxylate (CAS 1202030-11-2)
- 2-(6-Bromo-5-methoxy-1H-indol-3-yl)acetonitrile (CAS 1033715-38-6)
- tert-Butyl 3-hydroxy-3-(hydroxymethyl)pyrrolidine-1-carboxylate (CAS 1393732-46-1)
- Insulin Glargine (CAS 160337-95-1)
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