1-Iodo-2-(phenylethynyl)benzene CAS 109744-41-4
| CAS No. | 109744-41-4 |
| Molecular Formula | C14H9I |
| Molecular Weight | 304.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-Iodo-2-(phenylethynyl)benzene.
CATO supplies 1-Iodo-2-(phenylethynyl)benzene (CAS 109744-41-4), a certified reference material (molecular formula C14H9I, MW 304.13 g/mol) for analytical method development and quality control.
1-Iodo-2-(phenylethynyl)benzene (C14H9I) contains iodine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H9I |
| Molecular Weight | 304.13 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | I-containing |
Related Iodo Standards
- N-(3-Iodo-2-pyridyl)pivalamide (CAS 113975-31-8)
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- 4-(5-Iodo-3-methylpyridin-2-yl)morpholine (CAS 1704064-37-8)
- (4-Iodo-1H-pyrrol-2-yl)(piperidin-1-yl)methanone (CAS 1706433-21-7)
- 1-Iodo-4-(phenylethynyl)benzene (CAS 1849-28-1)
- Methyl 3-iodo-4-isopropylbenzoate (CAS 100127-58-0)
- Ethyl 4-iodo-3,5-dimethylbenzoate (CAS 1048677-10-6)
Recommended Standards
- 4-Amino-N-(4-iodophenyl)butanamide (CAS 1039879-31-6)
- N-(3-aminopropyl)-2-iodobenzamide (CAS 1016532-22-1)
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- Methyl 4-(4-iodophenyl)butanoate (CAS 756890-85-4)
- 2-Chloro-3-(chloromethyl)-4-(difluoromethyl)-5-methylpyridine (CAS 1805077-50-2)
- N-(1-(furan-2-yl)ethyl)propionamide (CAS 1147388-63-3)
- Methyl 4-amino-3-ethoxybenzoate (CAS 912839-50-0)
- 1-(2-methoxyethyl)-1H,4H,5H,6H,7H-[1,2,3]triazolo[4,5-c]pyridine (CAS 1481032-08-9)
- Azilsartan Impurity 129 (CAS CATO-C4X-1096129)
- 1-(1-Phenyl-2-(trimethylsilyl)ethyl)-1H-benzo[d][1,2,3]triazole (CAS 219700-98-8)
- 1-[(2,6-Dichlorophenyl)methyl]-N-methyl-6-oxo-N-phenyl-1,6-dihydropyridine-3-carboxamide (CAS 478065-99-5)
- 5-(3-Ethoxy-4-propoxybenzylidene)-2-phenylthiazolo[3,2-b][1,2,4]triazol-6(5H)-one (CAS 617694-33-4)
- 2-Amino-1-[4-(4-methoxyphenyl)piperazin-1-yl]ethanone (CAS 491837-75-3)
- Palmitoyl Hexapeptide-12 TFA salt (CAS 171263-26-6(Free Base))
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