cis-1-amino-3-(hydroxymethyl)cyclobutane-1-carboxylic acid hydrochloride CAS 109826-20-2
| CAS No. | 109826-20-2 |
| Molecular Formula | C6H11NO3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including cis-1-amino-3-(hydroxymethyl)cyclobutane-1-carboxylic acid hydrochloride.
CATO supplies cis-1-amino-3-(hydroxymethyl)cyclobutane-1-carboxylic acid hydrochloride (CAS 109826-20-2), a certified reference material (molecular formula C6H11NO3HCl, MW 181.62 g/mol) for analytical method development and quality control.
The molecular framework of cis-1-amino-3-(hydroxymethyl)cyclobutane-1-carboxylic acid hydrochloride (C6H11NO3HCl) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures cis-1-amino-3-(hydroxymethyl)cyclobutane-1-carboxylic acid hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H11NO3 HCl |
| Molecular Weight | 181.62 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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- 3-(4-Bromophenyl)-1-(2,4-dimethylphenyl)propan-1-one (CAS 898761-46-1)
- 3-[trans-2-methylcyclopropyl]prop-2-ynoic acid (CAS 2840435-98-3)
- 5-Amino-1-(5-(trifluoromethyl)pyridin-2-yl)-1h-pyrazole-4-carbonitrile (CAS 106792-02-3)
- (Glu9)-Exenatide (2-39) trifluoroacetate salt (CAS 196109-34-9)
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