3-(4-Chlorophenyl)pyrimidin-4(3H)-one CAS 109853-43-2
| CAS No. | 109853-43-2 |
| Molecular Formula | C10H7ClN2O |
| Molecular Weight | 206.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(4-Chlorophenyl)pyrimidin-4(3H)-one (CAS 109853-43-2), molecular formula C10H7ClN2O and molecular weight 206.63 g/mol, is a CATO reference standard with documented purity and traceability.
3-(4-Chlorophenyl)pyrimidin-4(3H)-one (C10H7ClN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-(4-Chlorophenyl)pyrimidin-4(3H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7ClN2O |
| Molecular Weight | 206.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorophenyl Standards
- 2-(4-Chlorophenyl)-3,4-dihydropyrimidin-4-one (CAS 106690-55-5)
- 2-(3-Chlorophenyl)-3,4-dihydropyrimidin-4-one (CAS 106690-56-6)
- 2-(2-Chlorophenyl)-3,4-dihydropyrimidin-4-one (CAS 1156241-13-2)
- 3-(3-Chlorophenyl)-4,5-dihydroisoxazole-5-carbonitrile (CAS 1160473-09-5)
- 3-(4-Chlorophenyl)-4,5-dihydroisoxazole-5-carbonitrile (CAS 1173119-75-9)
- 1-(4-Chlorophenyl)-1h-pyrazole-5-carbaldehyde (CAS 1266114-21-9)
- 1-(2-Chlorophenyl)-1H-pyrazole-5-carbaldehyde (CAS 1269291-08-8)
- 1-(3-Chlorophenyl)-1H-pyrazole-5-carbaldehyde (CAS 1269293-21-1)
Recommended Standards
- 8-Chloroquinoline-2-carboxamide (CAS 1070370-89-6)
- n-[(2-chloroquinolin-3-yl)methylidene]hydroxylamine (CAS 113232-02-3)
- 2-Chloro-4-(1-imidazolyl)benzaldehyde (CAS 1141669-45-5)
- 1-chloroisoquinoline-3-carboxamide (CAS 1152888-86-2)
- 2-Ethyl-8,9-dimethoxy-5-{[(2,4,6-trimethylphenyl)methyl]sulfanyl}-[1,2,4]triazolo[1,5-c]quinazoline (CAS 860650-33-5)
- 2-((2-(Azepan-1-yl)-2-oxoethyl)thio)-6-(trifluoromethyl)pyrimidin-4(3H)-one (CAS 899990-70-6)
- 2-Oxooxolan-3-yl prop-2-enoate (CAS 328249-37-2)
- H-Met-Phe-Gly-OH (H-4370.0250) (CAS 14492-15-0)
- 2-(4-Oxo-2-thioxo-3-thiazolidinyl)butanedioic acid (CAS 31316-80-0)
- 2-(Difluoromethoxy)-4,6-difluorobenzoic acid (CAS 1214326-16-5)
- 1,3-Dioxo-2-pyridin-4-ylmethyl-2,3-dihydro-1H-isoindole-5-carboxylic acid (CAS 356576-16-4)
- 4-Cyano-3-methylbenzoic Acid (CAS 73831-13-7)
- Methyl 2-chloro-5-fluoro-6-(piperidin-1-yl)nicotinate (CAS 1706436-03-4)
- Insulin Degludec Impurity 14 (CAS CATO-C4X-215714)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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