4-Fluoro-2-phenylquinoline CAS 109883-55-8
| CAS No. | 109883-55-8 |
| Molecular Formula | C15H10FN |
| Molecular Weight | 223.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Fluoro-2-phenylquinoline (CAS 109883-55-8) is a high-purity analytical reference standard with the molecular formula C15H10FN and a molecular weight of 223.25 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, 4-Fluoro-2-phenylquinoline is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 223.25 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H10FN |
| Molecular Weight | 223.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 5-Fluoro-2-phenylquinoline (CAS 1174197-78-4)
- 2-Fluoro-6-(naphthalen-1-yl)pyridine (CAS 1245648-43-4)
- 5-fluoro-2-(piperazin-1-yl)benzamide (CAS 1343756-13-7)
- 6-Fluoro-2-phenylquinoline (CAS 2558-26-1)
- 1-[2-fluoro-6-(morpholin-4-yl)phenyl]ethan-1-one (CAS 1019569-01-7)
- 1-(3-Fluoro-benzyl)-pyrrolidine-2-carboxylic acid (CAS 1026092-99-8)
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- 5-Fluoro-2-(piperidin-1-yl)benzoic acid (CAS 1096861-93-6)
Recommended Standards
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- Quinolin-6-yl methanesulfonate (CAS 1092513-18-2)
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- 4-Fluoropiperidine-2-carboxylic acid (CAS 1544167-75-0)
- 2-({[(3,4-dimethylphenyl)carbamoyl](phenyl)methyl}sulfanyl)acetic acid (CAS 339108-42-8)
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- Methyl 3-cyclohexylpropiolate (CAS 42134-60-1)
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- Semaglutide-d15 (CAS 910463-68-2(non-labelled))
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