Sumatriptan aminophenyl Impurity C05 CAS 109903-35-7
| CAS No. | 109903-35-7 |
| Molecular Formula | C8H12N2O2S |
| Molecular Weight | 200.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Sumatriptan aminophenyl Impurity C05 (CAS 109903-35-7, C8H12N2O2S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Sumatriptan aminophenyl Impurity C05 (C8H12N2O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 200.26 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C8H12N2O2S |
| Molecular Weight | 200.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Sumatriptan Standards
- Sumatriptan Impurity 11 (CAS 54476-52-7)
- Sumatriptan 5-Hydroxymethyl Impurity (CAS 334981-08-7)
- Sumatriptan-d (CAS 1346603-68-6)
- Sumatriptan Impurity 9 (CAS 85952-29-0)
- Sumatriptan cyanomethyl impurity, 98% (CAS 88918-76-7)
- Sumatriptan EP Impurity E (CAS 88919-22-6)
- Sumatriptan EP Impurity F (CAS 2074615-63-5)
- Sumatriptan Impurity 17 (CAS 88919-50-0)
Recommended Standards
- 5-Amino-2-ethylbenzene-1-sulfonamide (CAS 1094938-11-0)
- 2-Amino-3,5-dimethylbenzenesulfonamide (CAS 1119451-28-3)
- 3-((4-Methylthiazol-2-yl)amino)butanoic acid (CAS 1094695-16-5)
- 2-((6-Methyl-2-(methylthio)pyrimidin-4-yl)oxy)ethanol (CAS 112010-51-2)
- Avanafil Impurity 23 (CAS CATO-C4X-111823)
- Ampicillin Impurity 103 (CAS CATO-C4X-1443103)
- Lifitegrast Impurity 73 (CAS 2641788-18-1)
- Lansoprazole-d4 (CAS 934294-22-1)
- 1,4-Dimethyl-1h-1,2,3-triazole-5-carbaldehyde (CAS 1083223-99-7)
- 1-Methyl-4-(hydroxymethyl)-1,2,3,6-tetrahydropyridine (CAS 36166-75-3)
- 4-Chloro-N,N-diethyl-6-methoxy-1,3,5-triazin-2-amine (CAS 1722-21-0)
- C-(2-3-4-6-Tetra-O-acetyl-1-azido-1-deoxy-α-D-galactopyranosyl)formamide (CAS 180904-09-0)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (4-propylthiophen-2-yl)boronate (CAS 1416851-16-5)
- (9-D-Asp) Semaglutide X Sodium salt (CAS CATO-CPTD788617)
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