6-(3-tert-Butylphenoxy)-5-chloronicotinic acid CAS 1099115-90-8
| CAS No. | 1099115-90-8 |
| Molecular Formula | C16H16ClNO3 |
| Molecular Weight | 305.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-(3-tert-Butylphenoxy)-5-chloronicotinic acid.
CATO supplies 6-(3-tert-Butylphenoxy)-5-chloronicotinic acid (CAS 1099115-90-8), a certified reference material (molecular formula C16H16ClNO3, MW 305.76 g/mol) for analytical method development and quality control.
6-(3-tert-Butylphenoxy)-5-chloronicotinic acid (C16H16ClNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H16ClNO3 |
| Molecular Weight | 305.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related tert Standards
- 2-(4-Butylphenoxy)-N'-(furan-2-ylmethylene)acetohydrazide (CAS 303088-37-1)
- 4-(4-Tert-butylphenoxy)-3-nitrobenzaldehyde (CAS 726151-45-7)
- 3-[(4-tert-Butylphenoxy)methyl]-4-methoxybenzaldehyde (CAS 329222-86-8)
- 2-(4-tert-Butylphenoxy)-4-(dimethylamino)pyridine-3-carbonitrile (CAS 341967-06-4)
- 1-(4-Tert-butylphenoxy)-3-morpholin-4-ylpropan-2-ol (CAS 35151-89-4)
- 3-[3-(4-tert-Butylphenoxy)phenyl]-3-oxopropanenitrile (CAS 127389-38-2)
- 5-[(4-tert-Butylphenoxy)methyl]-4-ethyl-4H-1,2,4-triazole-3-thiol 667437-94-7 7780AE C15H21N3OS (CAS 667437-94-7)
- 3-(4-tert-Butylphenoxy)propane-1-sulfonyl chloride (CAS 1018288-96-4)
Recommended Standards
- 2-(4-Chloro-2-(hydroxymethyl)phenoxy)-N-(p-tolyl)acetamide (CAS 1097083-00-5)
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- 1094747-55-3 2-Chloro-N-(2,5-dimethoxyphenyl)-2-phenylacetamide MFCD13634278 (CAS 1094747-55-3)
- 2-(4-(4-Chlorophenyl)-6-oxopyrimidin-1(6H)-yl)-N-isopropylacetamide (CAS 1210763-93-1)
- 2-Cyanospiro[3.4]octane-2-carboxylic acid (CAS 1469129-54-1)
- n-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)pivalamide (CAS 532391-30-3)
- Benzyl 2-isopropyl-4-oxo-3,4-dihydropyridine-1(2H)-carboxylate (CAS 248919-73-5)
- (S)-1-(3-chloro-4-methylphenyl)pentan-1-amine (CAS 1213528-73-4)
- 1-Methyl-3-oxo-2,3,5,6,7,8-hexahydroisoquinoline-4-carbonitrile (CAS 17012-30-5)
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- N-(4-methoxy-3-methylbenzyl)propan-2-amine (CAS 1152936-93-0)
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- 6'-Bromo-1'H-spiro[cyclopropane-1,4'-isoquinoline]-1',3'(2'H)-dione (CAS 2167621-83-0)
- (Ser(PO?H?)2?2)-Tau Peptide (260-264) PAb Blocking trifluoroacetate salt (CAS 2022956-57-4)
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