1-(1,1-Difluoro-2-methylpropyl)-4-fluorobenzene CAS 1099597-91-7
| CAS No. | 1099597-91-7 |
| Molecular Formula | C10H11F3 |
| Molecular Weight | 188.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-(1,1-Difluoro-2-methylpropyl)-4-fluorobenzene (CAS 1099597-91-7), molecular formula C10H11F3 and molecular weight 188.19 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(1,1-Difluoro-2-methylpropyl)-4-fluorobenzene (C10H11F3) is characterized by fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 1-(1,1-Difluoro-2-methylpropyl)-4-fluorobenzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H11F3 |
| Molecular Weight | 188.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
Related Difluoro Standards
- 2,3-Difluoro-6-(methylthio)benzaldehyde (CAS 1394291-42-9)
- 2,6-Difluoro-4-(methylthio)benzaldehyde (CAS 1428234-70-1)
- 2,6-Difluoro-3-(methylthio)benzaldehyde (CAS 1428234-72-3)
- 2,3-Difluoro-4-(methylthio)benzaldehyde (CAS 1785584-66-8)
- 2,5-Difluoro-4-(methylthio)benzaldehyde (CAS 1826110-01-3)
- 2,4-Difluoro-3-(methylthio)benzaldehyde (CAS 1891309-76-4)
- 3,5-Difluoro-4-(methylthio)benzaldehyde (CAS 473299-49-9)
- (3,4-Difluoro-5-methoxyphenyl)boronic acid (CAS 49839-99-8)
Recommended Standards
- 1-Methyl-4-(3,3,3-trifluoropropyl)benzene (CAS 1099597-73-5)
- 1-(1,1-Difluorobutyl)-4-fluorobenzene (CAS 1099598-07-8)
- 1-Methyl-3-(3,3,3-trifluoropropyl)benzene (CAS 1099597-71-3)
- 1-(3-(1h-Tetrazol-5-yl)phenyl)ethan-1-one (CAS 1105679-23-9)
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Why CATO?
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