2-(6,8-Dibromo-2-methyl-4-oxo-1-phenyl-1,2-dihydroquinazolin-3(4H)-yl)ethyl 2-aminoacetate CAS 110022-76-9
| CAS No. | 110022-76-9 |
| Molecular Formula | C19H17Br2N3O3 |
| Molecular Weight | 495.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(6,8-Dibromo-2-methyl-4-oxo-1-phenyl-1,2-dihydroquinazolin-3(4H)-yl)ethyl 2-aminoacetate.
2-(6,8-Dibromo-2-methyl-4-oxo-1-phenyl-1,2-dihydroquinazolin-3(4H)-yl)ethyl 2-aminoacetate (CAS 110022-76-9) is a high-purity analytical reference standard with the molecular formula C19H17Br2N3O3 and a molecular weight of 495.16 g/mol.
2-(6,8-Dibromo-2-methyl-4-oxo-1-phenyl-1,2-dihydroquinazolin-3(4H)-yl)ethyl 2-aminoacetate (C19H17Br2N3O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(6,8-Dibromo-2-methyl-4-oxo-1-phenyl-1,2-dihydroquinazolin-3(4H)-yl)ethyl 2-aminoacetate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H17Br2N3O3 |
| Molecular Weight | 495.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Related Dibromo Standards
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- 5,5′-Dibromo-3,3′-bis(pentyloxy)-2,2′-bithiophene (CAS 1404166-45-5)
- 4,6-Dibromo-2-(3-iodophenyl)-2H-benzo[d][1,2,3]triazol-5-amine (CAS 1706437-39-9)
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Recommended Standards
- 4-(Bis(2-Bromoethyl)Amino)-Phenol 4-(alpha,alpha,alpha-Trifluoromethyl)Benzoate (CAS 22953-42-0)
- 3-Chloro-2-(3-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-1,2,4-triazol-3-yl}-1H-1,2,4-triazol-1-yl)-5-(trifluoromethyl)pyridine (CAS 303144-75-4)
- ddCTP (disodium) (CAS 132619-66-0)
- Ganciclovir triphosphate triethylamine salt (CAS 86761-38-8)
- (R)-(5,6,7,8-Tetrahydroindolizin-8-yl)methanamine (CAS 288588-14-7)
- 1-tert-Butyl 12-(2,5-dioxopyrrolidin-1-yl) dodecanedioate (CAS 2093277-79-1)
- 3-Aminopyrazole (CAS 1820-80-0)
- 1479463-90-5 2-[(2-Hydroxyethyl)amino]-N-methyl-N-(phenylmethyl)-acetamide (CAS 1479463-90-5)
- N-(2-Methoxyphenyl)-2-((3-methyl-4-oxo-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-7-yl)thio)acetamide (CAS 869073-92-7)
- Ethyl 2-ethylcyclopropanecarboxylate (CAS 115188-22-2)
- 8-Bromo-1-methylisoquinoline (CAS 1312905-33-1)
- 3-(4-(4-Chlorophenyl)-2-(ethylthio)oxazol-5-yl)propanoic acid (CAS 95727-51-8)
- 4-phenyl-3-butyn-2-one (CAS 1817-57-8)
- Semaglutide impurity 199 (CAS CATO-C4X-2226199)
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