4-(4-Chlorophenyl)-5-methyl-1H-pyrazol-3-amine hydrochloride CAS 1101780-51-1
| CAS No. | 1101780-51-1 |
| Molecular Formula | C10H10ClN3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(4-Chlorophenyl)-5-methyl-1H-pyrazol-3-amine hydrochloride (CAS 1101780-51-1), molecular formula C10H10ClN3HCl and molecular weight 244.12 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(4-Chlorophenyl)-5-methyl-1H-pyrazol-3-amine hydrochloride (C10H10ClN3HCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(4-Chlorophenyl)-5-methyl-1H-pyrazol-3-amine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H10ClN3 HCl |
| Molecular Weight | 244.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorophenyl Standards
- 2-(2-Chlorophenyl)-2-(pyrrolidin-1-yl)acetamide (CAS 1000340-02-2)
- N-(2-Chlorophenyl)-5-methyl-1-phenyl-1H-1,2,4-triazole-3-carboxamide (CAS 1000572-01-9)
- N-(2-Chlorophenyl)-5-oxo-1-(p-tolyl)-2,5-dihydro-1H-1,2,4-triazole-3-carboxamide (CAS 1000573-94-3)
- Methyl 1-(2-chlorophenyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazole-3-carboxylate (CAS 1000576-85-1)
- 1-(4-Chlorophenyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazole-3-carboxylic acid phenylamide (CAS 1000577-01-4)
- Benzyl 1-(4-chlorophenyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazole-3-carboxylate (CAS 1000577-09-2)
- 1-(2-Chlorophenyl)-5-oxo-N-phenyl-2,5-dihydro-1H-1,2,4-triazole-3-carboxamide (CAS 1000577-29-6)
- 2-(2-Chlorophenyl)-1-phenylethan-1-amine (CAS 1000615-44-0)
Recommended Standards
- 4-(2,3-Dihydroxypropoxy)benzaldehyde (CAS 64049-49-6)
- Ethyl 1-cyclopentyl-1H-pyrazole-3-carboxylate (CAS 1002535-19-4)
- 2-((4-Chlorophenyl)ethynyl)-5-nitrofuran (CAS 58246-12-1)
- Dodecahydrodibenzo[b,e][1,4]dioxine-4a,9a-diol (CAS 60308-50-1)
- 2-Amino-4-methoxybutanamide hydrochloride (CAS 1432677-68-3)
- 2-((Perchlorophenyl)thio)acetohydrazide (CAS 89978-39-2)
- (1R,2S)-2-(2-(2-nitrophenyl)-2-oxoethyl)cyclopentane-1-carboxylic acid (CAS 733740-76-6)
- (Z)-3-(4-Hydroxy-2-oxopent-3-en-1-yl)-1-methylpyrrolidine-2,5-dione (CAS 206562-86-9)
- 1-(4-Chlorobenzyl)-1H-imidazole (CAS 42032-27-9)
- Semaglutide Impurity 155 (x TFA Salt) (CAS CATO-C4X-2226155)
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