4-(4-Chlorophenyl)-2-(p-tolyl)oxazol-5(4H)-one CAS 110314-98-2
| CAS No. | 110314-98-2 |
| Molecular Formula | C16H12ClNO2 |
| Molecular Weight | 285.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(4-Chlorophenyl)-2-(p-tolyl)oxazol-5(4H)-one.
CATO supplies 4-(4-Chlorophenyl)-2-(p-tolyl)oxazol-5(4H)-one (CAS 110314-98-2), a certified reference material (molecular formula C16H12ClNO2, MW 285.72 g/mol) for analytical method development and quality control.
4-(4-Chlorophenyl)-2-(p-tolyl)oxazol-5(4H)-one (C16H12ClNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H12ClNO2 |
| Molecular Weight | 285.72 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorophenyl Standards
- Methyl 3-(4-chlorophenyl)-1H-indole-2-carboxylate (CAS 1134334-35-2)
- 2-(4-Chlorophenyl)-4-(p-tolyl)oxazol-5(4H)-one (CAS 114564-98-6)
- (4-Chlorophenyl)(5-methoxy-1H-indol-1-yl)methanone (CAS 30237-49-1)
- (E)-[(4-Chlorophenyl)methylidene]amino (2Z)-3-phenylprop-2-enoate (CAS 331462-10-3)
- 1-[(4-Chlorophenyl)methyl]-1H-indole-3-carboxylic acid (CAS 93548-89-1)
- 2-(4-Chlorophenyl)-6,8-dimethyl-4H-benzo[d][1,3]oxazin-4-one (CAS 301193-60-2)
- 2-[(3-Chlorophenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-1,3-dione (CAS 341965-94-4)
- 3-(4-Chlorophenyl)-5-(4-methoxyphenyl)isoxazole (CAS 24097-19-6)
Recommended Standards
- 5-Chloro-2-(3-methoxyphenyl)-1H-indole-3-carbaldehyde (CAS 1082409-57-1)
- 2-[(2-chloro-4-fluorophenyl)methyl]-4-methyl-1,3-thiazole-5-carboxylic acid (CAS 1110717-80-0)
- 7-Amino-3-chloro-2-methyl-5-(methylsulfonyl)pyrazolo[1,5-a]pyrimidine-6-carbonitrile (CAS 2798826-03-4)
- 2-{2-[(2-chloro-4-fluorophenyl)methyl]-1,3-thiazol-4-yl}acetic acid (CAS 1110717-81-1)
- Pazopanib Hydrochloride (CAS 635702-64-6)
- 3-Bromo-7-fluoro-1H-pyrrolo[3,2-c]pyridine (CAS 1190320-09-2)
- Propyl 4-oxo-4-(3-(thiazol-2-yl)thioureido)butanoate (CAS 875019-91-3)
- 3-(3-amino-1H-pyrazole-1-sulfonyl)benzonitrile (CAS 1306603-34-8)
- Methyl 4-chloro-2,2-dimethylpent-4-enoate (CAS 86799-85-1)
- Amlodipine EP Impurity G (CAS 43067-01-2)
- Purine nucleoside Phosphorylase, 200 units/mg (CAS 9030-21-1)
- Ethyl 3-(benzyloxy)benzoate (CAS 63888-94-8)
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- Peptide 438 (CAS CATO-CPTD788438)
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