Omeprazole EP Impurity B CAS 110374-16-8
| CAS No. | 110374-16-8 |
| Molecular Formula | C16H17N3O2S |
| Molecular Weight | 315.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Omeprazole EP Impurity B is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Omeprazole EP Impurity B (CAS 110374-16-8, C16H17N3O2S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Omeprazole EP Impurity B (C16H17N3O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Omeprazole EP Impurity B meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H17N3O2S |
| Molecular Weight | 315.39 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Omeprazole Standards
- Omeprazole Impurity 37 (CAS 73590-60-0)
- Omeprazole Impurity 43 (CAS 151602-50-5)
- Omeprazole Impurity 7 (CAS 103877-02-7)
- Omeprazole Impurity 46 (CAS CATO-C4X-125546)
- Omeprazole Impurity 47 (CAS CATO-C4X-125547)
- Omeprazole EP Impurity G (CAS 125656-83-9)
- Omeprazole EP Impurity F (CAS 125656-82-8)
- Omeprazole Impurity 12 (CAS CATO-C4X-125512)
Recommended Standards
- Ticagrelor impurity 99 (CAS CATO-C4X-109399)
- Apremilast impurity 64 (CAS CATO-C4X-100964)
- Esomeprazole Impurity 58 (CAS CATO-C4X-111258)
- Apremilast Impurity 51 (CAS 2097600-16-1)
- Palonosetron Impurity N15 (CAS 1796933-62-4)
- Drospirenone Impurity 13(Mixture of Diastereomers) (CAS CATO-C4X-162413)
- Amlodipine Impurity 112 (CAS CATO-C4X-1095112)
- Methyl 4-isothiocyanato-3-methylbenzoate (CAS 1360960-70-8)
- Ethyl 5-(p-tolylthio)-1,2,3-thiadiazole-4-carboxylate (CAS 306977-04-8)
- 2-(4-Methoxyphenyl)-8,8-dimethyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine (CAS 1416438-88-4)
- 5-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-5-oxopentanoic acid (CAS 620931-00-2)
- 2-Azido-1-(4-methoxy-3-sulfonamidophenyl)-1-propanone (CAS 1189968-86-2)
- 1-(pyridin-2-yl)-1H-pyrrolo[3,2-b]pyridine-3-carboxylic acid (CAS 2105951-90-2)
- Tau Peptide (294-305) (human) trifluoroacetate salt (CAS 1428135-29-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com