2-(4-Chlorophenyl)-2-(diethylamino)acetic acid CAS 1103977-69-0
| CAS No. | 1103977-69-0 |
| Molecular Formula | C12H16ClNO2 |
| Molecular Weight | 241.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(4-Chlorophenyl)-2-(diethylamino)acetic acid (C12H16ClNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2-(4-Chlorophenyl)-2-(diethylamino)acetic acid (CAS 1103977-69-0), molecular formula C12H16ClNO2 and molecular weight 241.71 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H16ClNO2 |
| Molecular Weight | 241.71 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorophenyl Standards
- ETHYL 2-(3-CHLOROPHENYL)-2-(DIMETHYLAMINO)ACETATE (CAS 1007885-46-2)
- ETHYL 2-(2-CHLOROPHENYL)-2-(DIMETHYLAMINO)ACETATE (CAS 1007885-47-3)
- ETHYL 2-(4-CHLOROPHENYL)-2-(DIMETHYLAMINO)ACETATE (CAS 1007885-48-4)
- Methyl 3-{[(2-chlorophenyl)methyl]amino}butanoate (CAS 1026959-14-7)
- 2-(2-Chlorophenyl)-2-(diethylamino)acetic acid (CAS 1101768-16-4)
- Methyl 3-{[(2-chlorophenyl)methyl]amino}-2-methylpropanoate (CAS 1154153-25-9)
- Methyl 3-{[(4-chlorophenyl)methyl]amino}-2-methylpropanoate (CAS 1154286-85-7)
- Methyl 3-{[(4-chlorophenyl)methyl]amino}butanoate (CAS 1155161-13-9)
Recommended Standards
- N-(4-Chloro-2-methoxyphenyl)pivalamide (CAS 113137-29-4)
- Methyl 4-((2-chlorobenzyl)amino)butanoate (CAS 1096859-39-0)
- Methyl 4-((4-chlorobenzyl)amino)butanoate (CAS 1096805-24-1)
- 4-Chloro-N-(4-methoxy-2-methylphenyl)butanamide (CAS 1092380-15-8)
- 5-(1-Ethyl-1H-pyrazol-4-yl)-3-methylpyrazolo[1,5-a]pyrimidine-7-carboxylic acid (CAS 1443279-53-5)
- Fmoc-Thr(SO3Na)-OH (CAS 160112-18-5)
- N-[1-(3-Cyanopyridin-2-yl)piperidin-4-yl]acetamide (CAS 1160261-64-2)
- (R)-4,4-diethoxy-2-(hydroxymethyl)butyl acetate (CAS 144461-19-8)
- 1,3-Bis(2-fluorobenzyl)piperazin-2-one (CAS 1218047-88-1)
- (S)-1-Methyl-1,2,3,4-tetrahydrobenzo[4,5]imidazo[1,2-a]pyrazine (CAS 135875-08-0)
- (2R,3R,4S,5R)-2,3,4,5-Tetrahydroxy-3-methylhexanal (CAS 69351-79-7)
- Methyl 2-amino-5-(2-phenylethyl)-1,3-thiazole-4-carboxylate (CAS 710348-76-8)
- Piperazin-2-yl(pyrrolidin-1-yl)methanone (CAS 123866-43-3)
- D-allo-Thr7-Semaglutide (CAS CATO-C4X-2226242)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com