5-Iodonaphthalene-1-sulfonyl chloride CAS 110448-35-6

Description

The occurrence of 5-Iodonaphthalene-1-sulfonyl chloride is closely related to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/iodine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

5-Iodonaphthalene-1-sulfonyl chloride (CAS 110448-35-6), molecular formula C10H6ClIO2S and molecular weight 352.58 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 5-Iodonaphthalene-1-sulfonyl chloride (C10H6ClIO2S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

As a certified reference material (CRM), 5-Iodonaphthalene-1-sulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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