2-Chloro-1-(5-fluoro-2-pyridyl)ethanone CAS 1104606-44-1
| CAS No. | 1104606-44-1 |
| Molecular Formula | C7H5ClFNO |
| Molecular Weight | 173.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-1-(5-fluoro-2-pyridyl)ethanone.
CATO supplies 2-Chloro-1-(5-fluoro-2-pyridyl)ethanone (CAS 1104606-44-1), a certified reference material (molecular formula C7H5ClFNO, MW 173.57 g/mol) for analytical method development and quality control.
2-Chloro-1-(5-fluoro-2-pyridyl)ethanone (C7H5ClFNO) contains an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H5ClFNO |
| Molecular Weight | 173.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 4-Chloro-2-fluorobenzamide (CAS 104326-93-4)
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- N-(2-chloro-3-fluorophenyl)formamide (CAS 1070892-66-8)
- 1-(2-Chloro-3-fluoropyridin-4-yl)ethanone (CAS 1236770-00-5)
- 1-(4-Chloro-6-fluoropyridin-3-yl)ethan-1-one (CAS 1240604-54-9)
- 1-(6-Chloro-3-fluoropyridin-2-yl)ethanone (CAS 1256787-63-9)
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