N-(4-amino-2-methoxyphenyl)thiophene-2-carboxamide CAS 110506-36-0

Description

The occurrence of N-(4-amino-2-methoxyphenyl)thiophene-2-carboxamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies N-(4-amino-2-methoxyphenyl)thiophene-2-carboxamide (CAS 110506-36-0), a certified reference material (molecular formula C12H12N2O2S, MW 248.30 g/mol) for analytical method development and quality control.

Structurally, N-(4-amino-2-methoxyphenyl)thiophene-2-carboxamide (C12H12N2O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 248.30 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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