1-(4-(Difluoromethoxy)phenyl)-5-(p-tolyl)-1h-imidazole-2-thiol CAS 1105189-15-8
| CAS No. | 1105189-15-8 |
| Molecular Formula | C17H14F2N2OS |
| Molecular Weight | 332.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(4-(Difluoromethoxy)phenyl)-5-(p-tolyl)-1h-imidazole-2-thiol (CAS 1105189-15-8) is a high-purity analytical reference standard with the molecular formula C17H14F2N2OS and a molecular weight of 332.37 g/mol.
The molecular framework of 1-(4-(Difluoromethoxy)phenyl)-5-(p-tolyl)-1h-imidazole-2-thiol (C17H14F2N2OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-(4-(Difluoromethoxy)phenyl)-5-(p-tolyl)-1h-imidazole-2-thiol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H14F2N2OS |
| Molecular Weight | 332.37 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Difluoromethoxy Standards
- 1-(4-(Difluoromethoxy)phenyl)-2-(methylthio)-5-phenyl-1H-imidazole (CAS 1226429-09-9)
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- 6-[4-(difluoromethoxy)phenyl]-1-ethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1011396-74-9)
- 6-[4-(difluoromethoxy)phenyl]-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1011399-85-1)
- Methyl 6-(4-(difluoromethoxy)phenyl)-3-methylisoxazolo[5,4-b]pyridine-4-carboxylate (CAS 1011396-51-2)
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- 1-(6,7-Bis(difluoromethoxy)naphthalen-2-yl)-2-methylpropan-1-one (CAS 1313885-94-7)
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Recommended Standards
- Butamifos (CAS 36335-67-8)
- 2-(4-Methoxybenzamido)-4,5,6,7-tetrahydrobenzo[d]thiazole-4-carboxylic acid (CAS 1105190-70-2)
- Vericiguat Impurity 82 (CAS CATO-C4X-289682)
- (2E)-3-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)prop-2-en-1-one (CAS 1152162-39-4)
- (S)-2-((DiiSopropoxyphosphoryl)amino)propanoic acid (CAS 110484-60-1)
- 1-(4-Chloro-3-methylphenyl)but-3-en-1-ol (CAS 842123-74-4)
- 3-([1,1'-Biphenyl]-4-yl)-5-(4-(tert-butyl)phenyl)-4H-1,2,4-triazole (CAS 1196894-07-1)
- 3-Methylcyclopentane-1-sulfonamide (CAS 1341961-86-1)
- 3-(tert-Butoxy)-4-cyclopropoxy-2-methylpyridine (CAS 1243284-30-1)
- N-[3-Sulfanyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-4-yl]benzamide (CAS 118159-05-0)
- 2-Amino-4-bromo-5-chlorophenol (CAS 1037298-14-8)
- 2-(1,1-Dioxido-3-oxobenzo[d]isothiazol-2(3H)-yl)-N-(3-methoxypropyl)acetamide (CAS 799257-07-1)
- N’-(1-isopropyl-1H-pyrazol-5-yl)-N-methylbenzenecarboximidamide (CAS 1006463-43-9)
- Nonapeptide-1 (CAS 158563-45-2)
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