1-(4-Fluorobenzyl)-4-(3-(thiophen-2-yl)-1,2,4-oxadiazol-5-yl)pyrrolidin-2-one CAS 1105196-63-1
| CAS No. | 1105196-63-1 |
| Molecular Formula | C17H14FN3O2S |
| Molecular Weight | 343.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 1-(4-Fluorobenzyl)-4-(3-(thiophen-2-yl)-1,2,4-oxadiazol-5-yl)pyrrolidin-2-one (CAS 1105196-63-1), a certified reference material (molecular formula C17H14FN3O2S, MW 343.38 g/mol) for analytical method development and quality control.
1-(4-Fluorobenzyl)-4-(3-(thiophen-2-yl)-1,2,4-oxadiazol-5-yl)pyrrolidin-2-one (C17H14FN3O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 1-(4-Fluorobenzyl)-4-(3-(thiophen-2-yl)-1,2,4-oxadiazol-5-yl)pyrrolidin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H14FN3O2S |
| Molecular Weight | 343.38 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Fluorobenzyl Standards
- 1-(2-Fluorobenzyl)-4-(3-(thiophen-2-yl)-1,2,4-oxadiazol-5-yl)pyrrolidin-2-one (CAS 1170992-86-5)
- N-((5-((2-Fluorobenzyl)thio)-1,3,4-oxadiazol-2-yl)methyl)benzamide (CAS 941875-46-3)
- N-((5-((4-Fluorobenzyl)thio)-1,3,4-oxadiazol-2-yl)methyl)benzamide (CAS 941922-79-8)
- 2-((4-Fluorobenzyl)amino)-4-(4-isopropylphenyl)-4-oxobutanoic acid (CAS 1024697-65-1)
- N-(4-Fluorobenzyl)-4-(2-methoxyphenyl)tetrahydro-2H-pyran-4-carboxamide (CAS 1091138-65-6)
- 1-(4-Fluorobenzyl)-3-((1-(methylsulfonyl)piperidin-4-yl)methyl)urea (CAS 1234972-02-1)
- 1-Ethyl-2-((4-fluorobenzyl)thio)-5-(4-methoxyphenyl)-1H-imidazole (CAS 1207045-53-1)
- 3-((4-Fluorobenzyl)thio)-6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 894048-34-1)
Recommended Standards
- 1,3-Diethyl 2-{[(3-methyl-1-phenyl-1H-pyrazol-5-yl)amino]methylidene}propanedioate (CAS 110299-41-7)
- ((4-Methoxyphenyl){2-oxo-2-[(2-pyridin-2-ylethyl)-amino]ethyl}amino)acetic acid 1142215-84-6 9471AC C18H21N3O4 (CAS 1142215-84-6)
- 2-(Benzyloxy)-7-phenylisoquinoline-1,3(2H,4H)-dione (CAS 1092801-83-6)
- 2-((S)-2-((S)-1-(tert-Butoxycarbonyl)pyrrolidine-2-carboxamido)propanamido)acetic acid (CAS 108653-40-3)
- 3-(5-CHLORO-1H-INDOL-3-YL)-3-OXOPROPANENITRILE (CAS 1384512-44-0)
- N-((1H-Indol-2-yl)methyl)propan-2-amine (CAS 106024-59-3)
- ((2R,5S)-5-(4-Amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl)methyl tetrahydrogen triphosphate (CAS 145819-92-7)
- 2,5-difluoro-4-iodobenzoic acid (CAS 501433-01-8)
- 1-(4-(3,5-Dimethyl-1H-pyrazol-1-yl)phenyl)-N-methylmethanamine (CAS 937796-07-1)
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- Irinotecan Impurity N1 (CAS 1026078-50-1)
- 3, 4- Oxazolidinedicarboxy lic Acid 3- (1, 1-Dimethylethyl) Ester (CAS 1253789-16-0)
- Nerandomilast impurity 30 (CAS CATO-C4X-347330)
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