7-(3-Fluorophenyl)-3-(3-methoxybenzyl)thieno[3,2-d]pyrimidin-4(3H)-one CAS 1105211-80-0
| CAS No. | 1105211-80-0 |
| Molecular Formula | C20H15FN2O2S |
| Molecular Weight | 366.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 7-(3-Fluorophenyl)-3-(3-methoxybenzyl)thieno[3,2-d]pyrimidin-4(3H)-one is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
7-(3-Fluorophenyl)-3-(3-methoxybenzyl)thieno[3,2-d]pyrimidin-4(3H)-one (CAS 1105211-80-0) is a high-purity analytical reference standard with the molecular formula C20H15FN2O2S and a molecular weight of 366.41 g/mol.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, 7-(3-Fluorophenyl)-3-(3-methoxybenzyl)thieno[3,2-d]pyrimidin-4(3H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 366.41 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 7-(3-Fluorophenyl)-3-(3-methoxybenzyl)thieno[3,2-d]pyrimidin-4(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H15FN2O2S |
| Molecular Weight | 366.41 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Fluorophenyl Standards
- 1-(4-(2-Fluorophenyl)thiazol-2-yl)-4-(4-methoxyphenyl)-1H-pyrazol-5-amine (CAS 955963-46-9)
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- 4-(4-Fluorophenyl)-1-(4-(4-methoxyphenyl)thiazol-2-yl)-1H-pyrazol-5-amine (CAS 955966-79-7)
- (2Z)-2-(2-Fluorophenyl)-3-[4-(3-formyl-1H-indol-1-yl)phenyl]prop-2-enenitrile (CAS 692287-42-6)
- Methyl 4-{4-[4-(4-fluorophenyl)-2-pyrimidinyl]phenoxy}butanoate (CAS 477856-81-8)
- 1-(4-Fluorophenyl)-2-[(2-{[2-(4-fluorophenyl)-2-oxoethyl]sulfanyl}ethyl)sulfanyl]ethan-1-one (CAS 271772-52-2)
- 4-((4-(N-(4-fluorophenyl)sulfamoyl)phenyl)amino)-4-oxobutanoic acid (CAS 383-43-7)
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Recommended Standards
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- N-Boc-4-nitro-L-phenylalanine-T-butyl ester (CAS 116366-27-9)
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- 5-(Methoxymethyl)-2,3-dihydro-1,3,4-oxadiazol-2-one (CAS 1711-90-6)
- 5-Methyl-2-(4-methyl-1h-pyrazol-1-yl)aniline (CAS 1184546-75-5)
- Alectinib impurity 24 (CAS 1256585-32-6)
- 4-Cyano-3-(difluoromethyl)-2-methoxy-5-(trifluoromethyl)pyridine (CAS 1806958-35-9)
- 6-Bromo-8,9-dihydro-7H-cyclopenta[c][1,2,4]triazolo[1,5-a]pyridine (CAS 2919363-64-5)
- 3-(4-Chlorobenzylidene)-N-(p-tolyl)-3H-indol-2-amine (CAS 139678-46-9)
- D-Ile27-Tirzepatide (CAS CATO-CPTD788907)
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