N-(2,4-Dimethylphenyl)-2-{4-oxo-7-phenyl-3H,4H-thieno[3,2-d]pyrimidin-3-yl}acetamide CAS 1105223-83-3
| CAS No. | 1105223-83-3 |
| Molecular Formula | C22H19N3O2S |
| Molecular Weight | 389.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(2,4-Dimethylphenyl)-2-{4-oxo-7-phenyl-3H,4H-thieno[3,2-d]pyrimidin-3-yl}acetamide.
N-(2,4-Dimethylphenyl)-2-{4-oxo-7-phenyl-3H,4H-thieno[3,2-d]pyrimidin-3-yl}acetamide (CAS 1105223-83-3), molecular formula C22H19N3O2S and molecular weight 389.47 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-(2,4-Dimethylphenyl)-2-{4-oxo-7-phenyl-3H,4H-thieno[3,2-d]pyrimidin-3-yl}acetamide (C22H19N3O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N-(2,4-Dimethylphenyl)-2-{4-oxo-7-phenyl-3H,4H-thieno[3,2-d]pyrimidin-3-yl}acetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H19N3O2S |
| Molecular Weight | 389.47 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related N Standards
- N-(2,6-Dimethylphenyl)-2-{4-oxo-7-phenyl-3H,4H-thieno[3,2-d]pyrimidin-3-yl}acetamide (CAS 1105223-88-8)
- N-(2,5-dimethylphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide (CAS 1105235-28-6)
- N-(3,4-Dimethylphenyl)-2-{4-oxo-7-phenyl-3H,4H-thieno[3,2-d]pyrimidin-3-yl}acetamide (CAS 1105235-79-7)
- N-(2,4-Dimethylphenyl)-2-((3-(2-hydroxyethyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide (CAS 1798672-20-4)
- N-(2,3-Dimethylphenyl)-2-((3-ethyl-6-methyl-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide (CAS 851409-39-7)
- N-(2,4-Dimethylphenyl)-2-((3-ethyl-6-methyl-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide (CAS 851409-41-1)
- N-(2,3-dimethylphenyl)-3-(3-(3-(trifluoromethyl)phenyl)-1,2,4-oxadiazol-5-yl)propanamide (CAS 866040-01-9)
- 3-[4-(2,6-dimethylphenyl)-5-sulfanyl-4H-1,2,4-triazol-3-yl]-N,N-dimethylbenzene-1-sulfonamide (CAS 380436-89-5)
Recommended Standards
- (R)-4-((tritylthio)methyl)oxazolidine-2,5-dione (CAS 1051374-19-6)
- 2-(4-(2-Fluorophenyl)piperazin-1-yl)-N,N-diphenylacetamide (CAS 1024400-18-7)
- N-[(4-Methylphenyl)methyl]-2-{4-oxo-7-phenyl-3H,4H-thieno[3,2-d]pyrimidin-3-yl}acetamide (CAS 1105234-85-2)
- 1,2-Bis-isodecyl-4-isotridecyl Trimellitate (CAS 70225-05-7)
- Ethyl 1-amino-2,3-dihydro-1h-indene-1-carboxylate hydrochloride (CAS 1306606-03-0)
- Ethyl 3-methylhexanoate (CAS 41692-47-1)
- tert-Butyl (6s)-6-(aminomethyl)-2,2-dimethylmorpholine-4-carboxylate (CAS 1416444-89-7)
- 1-(2-Fluoroethyl)-N-((5-fluorothiophen-2-yl)methyl)-3-methyl-1H-pyrazol-4-amine hydrochloride (CAS 1855937-24-4)
- 4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)benzoic Acid Hydrochloride (CAS 887399-47-5)
- cis-5-Ethoxycarbonyl-1H-hexahydropyrrolo[3,4-b]pyrrole (CAS 894854-14-9)
- 4-Bromo-3-chloropicolinaldehyde (CAS 1289114-25-5)
- Cyclohexanemethanol, .alpha.,3,3-trimethyl- (CAS 25225-09-6)
- 2-Hexadecyloxyethanol (CAS 2136-71-2)
- Q-Peptide trifluoroacetate salt (CAS 1361235-89-3)
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