3-(2-Fluorobenzyl)-6-(4-fluorophenyl)pyrimidin-4(3H)-one CAS 1105236-06-3
| CAS No. | 1105236-06-3 |
| Molecular Formula | C17H12F2N2O |
| Molecular Weight | 298.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(2-Fluorobenzyl)-6-(4-fluorophenyl)pyrimidin-4(3H)-one (C17H12F2N2O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies 3-(2-Fluorobenzyl)-6-(4-fluorophenyl)pyrimidin-4(3H)-one (CAS 1105236-06-3), a certified reference material (molecular formula C17H12F2N2O, MW 298.29 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H12F2N2O |
| Molecular Weight | 298.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluorobenzyl Standards
- 2-(4-Fluorobenzyl)-5-methyl-2H-1,2,6-thiadiazine-4-carboxylic acid 1,1-dioxide (CAS 1443978-73-1)
- 2-(2-fluorobenzyl)-5-methyl-2H-1,2,6-thiadiazine-4-carboxylic acid 1,1-dioxide (CAS 1443978-88-8)
- 5-{[(2-Fluorobenzyl)sulfonyl]methyl}-2-furoic acid (CAS 899710-21-5)
- N-(2-Fluorobenzyl)-6-(1H-1,2,4-triazol-1-yl)pyridazine-3-carboxamide (CAS 1448033-45-1)
- Ethyl 1-(3-fluorobenzyl)-1H-pyrrolo[2,3-c]pyridine-2-carboxylate (CAS 920978-82-1)
- 1-(2-Fluorobenzyl)-5-(pyridin-4-yl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1329922-38-4)
- 1-(2-Fluorobenzyl)-5-(pyridin-2-yl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1338689-81-8)
- 4-(2-(2-Fluorobenzyl)-2H-tetrazol-5-yl)benzoic acid (CAS 708290-59-9)
Recommended Standards
- 3-(3,4-Dimethoxyphenyl)-7-hydroxy-2h-chromen-2-one (CAS 109598-98-3)
- 5-((3-Nitrophenoxy)methyl)-3-phenyl-4,5-dihydroisoxazole (CAS 113296-49-4)
- Pinocembrin, 7-acetate (CAS 109592-60-1)
- 4-(4-(Ethoxycarbonyl)benzoyl)benzoic acid (CAS 113709-91-4)
- (2R)-2-(5-Hexen-1-yloxy)propanoic acid (CAS 1218998-90-3)
- 1-(4-Fluoro-3-methylphenyl)guanidine (CAS 754214-02-3)
- 3-(1,3-Benzodioxol-5-yl)propanohydrazide (CAS 88368-72-3)
- 2-(3,5-Dimethoxyphenyl)-2,6-diazaspiro[3.3]Heptane (CAS 2306278-56-6)
- 3-(5-bromanylpyridin-3-yl)prop-2-yn-1-ol 3-(5-bromo-3-pyridinyl)-2-propyn-1-ol 873302-37-5 A842088 (CAS 873302-37-5)
- 2-(6-(Aminomethyl)pyridin-3-yl)acetic acid (CAS 34984-17-3)
- 4-Chloro-2-fluoro-3-(3-pyrrolinomethyl) benzophenone (CAS 898749-44-5)
- 4-Methyl-5-(pyrrolidin-2-yl)pyridin-2-amine (CAS 1270431-81-6)
- 5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine (CAS 99969-13-8)
- Neuroendocrine Regulatory Peptide-1 (human) (H-6622.1000) (CAS 954420-50-9)
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