Arbidol Impurity 25 CAS 110543-98-1
| CAS No. | 110543-98-1 |
| Molecular Formula | C15H15Br2NO4 |
| Molecular Weight | 433.09 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Arbidol Impurity 25 (C15H15Br2NO4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Arbidol Impurity 25 (CAS 110543-98-1, C15H15Br2NO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Arbidol Impurity 25 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H15Br2NO4 |
| Molecular Weight | 433.09 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Arbidol Standards
- Arbidol Impurity 51 (CAS 2062260-55-1)
- Arbidol impurity 45 (CAS CATO-C4X-112945)
- Arbidol Impurity 24 (CAS CATO-C4X-112924)
- Arbidol Impurity 22 (CAS CATO-C4X-112922)
- Arbidol Impurity 32 (CAS CATO-C4X-112932)
- Arbidol impurity 44 (CAS CATO-C4X-112944)
- Arbidol Impurity 2 (CAS 131707-24-9)
- Arbidol Impurity 26 (CAS CATO-C4X-112926)
Recommended Standards
- 6-bromo-2-[(E)-2-(4-bromophenyl)ethenyl]quinoline-4-carboxylic acid (CAS 926235-74-7)
- 1-(4-Bromo-3-(perfluoropropyl)-5-phenyl-1H-pyrazol-1-yl)ethan-1-one (CAS 231955-61-6)
- 4-Bromo-3,3,4,4-tetrafluorobutyl (2,2,3,4,4,4-hexafluorobutyl) carbonate (CAS 1980034-73-8)
- 2,3,4,5,6-Pentakis(trifluoromethyl)aniline (CAS 58956-76-6)
- Budesonide Impurity 51 (CAS CATO-C4X-138951)
- Orlistat Impurity 2 (CAS 104872-28-8)
- Regadenoson Impurity 4 (CAS CATO-C4X-19854)
- methyl 3-(methylsulfanyl)butanoate (CAS 207983-28-6)
- ethyl 2-(4-nitrophenyl)(d2)acetate (CAS 1376709-86-2)
- (3R,4S,5R)-tert-butyl 3-methoxy-5-methyl-4-(methylamino)heptanoate hydrochloride (CAS 130273-11-9)
- 1-(5-Isopropyl-1h-1,2,4-triazol-3-yl)-2,2-dimethylpropan-1-amine (CAS 1250815-77-0)
- 3H-[1,2,3]Triazolo[4,5-b]pyridine-3-carboxamide (CAS 89875-92-3)
- Carbamoyltryptophan (CAS 98299-50-4)
- Semaglutide Impurity 115 (CAS CATO-C4X-2226115)
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