5-(4-Fluoro-3-(trifluoromethyl)phenyl)pyridin-2-amine CAS 1110656-35-3

Description

Compared with other compounds in its class, the molecular weight of 256.20 g/mol gives 5-(4-Fluoro-3-(trifluoromethyl)phenyl)pyridin-2-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

5-(4-Fluoro-3-(trifluoromethyl)phenyl)pyridin-2-amine (CAS 1110656-35-3), molecular formula C12H8F4N2 and molecular weight 256.20 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 5-(4-Fluoro-3-(trifluoromethyl)phenyl)pyridin-2-amine (C12H8F4N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 5-(4-Fluoro-3-(trifluoromethyl)phenyl)pyridin-2-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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