6-Chloro-5-(trifluoromethyl)nicotinic Acid CAS 1110782-41-6
| CAS No. | 1110782-41-6 |
| Molecular Formula | C7H3ClF3NO2 |
| Molecular Weight | 225.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 6-Chloro-5-(trifluoromethyl)nicotinic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
6-Chloro-5-(trifluoromethyl)nicotinic Acid (CAS 1110782-41-6) is a high-purity analytical reference standard with the molecular formula C7H3ClF3NO2 and a molecular weight of 225.55 g/mol.
Based on its molecular formula C7H3ClF3NO2, 6-Chloro-5-(trifluoromethyl)nicotinic Acid contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 225.55 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C7H3ClF3NO2 |
| Molecular Weight | 225.55 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 4-Chloro-2-(trifluoromethyl)nicotinic acid (CAS 1018678-39-1)
- 4-Chloro-6-(trifluoromethyl)picolinic acid (CAS 1060810-65-2)
- 4-chloro-6-(trifluoromethyl)nicotinic acid (CAS 1060810-66-3)
- 5-Chloro-2-nitrobenzotrifluoride (CAS 118-83-2)
- 5-Chloro-3-(trifluoromethyl)picolinic acid (CAS 1198475-43-2)
- 4-Chloro-5-(trifluoromethyl)nicotinic Acid (CAS 1211520-84-1)
- 4-Chloro-5-(trifluoromethyl)picolinic acid (CAS 1211591-26-2)
- 4-Chloro-3-(trifluoromethyl)picolinic acid (CAS 1226890-59-0)
Recommended Standards
- 2-(2-Bromoethyl)-4-chlorothiophene (CAS 1519791-48-0)
- SEL7RD3BBR 7154-66-7 Benzoyl chloride, 2-bromo- (9CI) 2-Bromobenzoyl chloride Benzoyl chloride, o-bromo- BRN 0508506 EINECS 230-507-4 NSC 73706 4-09-00-01013 (Beilstein Handbook Reference) UNII-SEL7RD3BBR (CAS 7154-66-7)
- 586-75-4 Benzoyl chloride, 4-bromo- 4-Bromobenzoyl chloride Benzoyl chloride, p-bromo- p-Bromobenzoyl chloride p-Bromobenzoyl chloride, p-bromo- EINECS 209-580-1 NSC 7091 (CAS 586-75-4)
- 2-Chloro-3-(trifluoromethyl)isonicotinic Acid (CAS 1227587-24-7)
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- Semaglutide impurity 255 (CAS CATO-C4X-2226255)
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