5-(2,5-Difluorophenyl)pyrimidin-2-ol CAS 1111108-68-9
| CAS No. | 1111108-68-9 |
| Molecular Formula | C10H6F2N2O |
| Molecular Weight | 208.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(2,5-Difluorophenyl)pyrimidin-2-ol (C10H6F2N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
5-(2,5-Difluorophenyl)pyrimidin-2-ol (CAS 1111108-68-9), molecular formula C10H6F2N2O and molecular weight 208.16 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-(2,5-Difluorophenyl)pyrimidin-2-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H6F2N2O |
| Molecular Weight | 208.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluorophenyl Standards
- 5-(2,6-difluorophenyl)furan-2-carbaldehyde (CAS 1094399-13-9)
- 6-(2,4-Difluorophenyl)pyridazin-3-ol (CAS 1105194-20-4)
- 5-(2,3-Difluorophenyl)pyrimidin-2-ol (CAS 1111103-65-1)
- 5-(2,4-Difluorophenyl)pyrimidin-4-ol (CAS 1111107-55-1)
- 5-(2,4-Difluorophenyl)pyrimidin-2-ol (CAS 1111107-95-9)
- 5-(3,5-Difluorophenyl)pyrimidin-2-ol (CAS 1111108-14-5)
- 5-(2,6-Difluorophenyl)pyrimidin-2-ol (CAS 1111108-20-3)
- 5-(3,4-Difluorophenyl)pyrimidin-2-ol (CAS 1111108-31-6)
Recommended Standards
- 5-(2,3-difluorophenyl)furan-2-carbaldehyde (CAS 1126635-06-0)
- 2-Methoxyethyl trifluoromethanesulfonate (CAS 112981-50-7)
- 1-(2,4-Difluorophenyl)-1h-pyrazole-4-carbaldehyde (CAS 1134705-53-5)
- 3-(2,6-Difluorophenyl)-1h-pyrazole-4-carbaldehyde (CAS 1152542-08-9)
- 2-Methyl-4-propoxybenzaldehyde (CAS 883531-90-6)
- 4-Chloro-2-(pyridin-4-yl)-5-(p-tolyl)thieno[2,3-d]pyrimidine (CAS 885460-94-6)
- 4-Chloro-6-vinylpyrimidine (CAS 2098024-71-4)
- 1-Chloro-4-nitro-2-propoxybenzene (CAS 76464-50-1)
- 3-methyl-4-(piperidin-4-yl)morpholine dihydrochloride (CAS 1803609-10-0)
- 1-(Methylsulfonyl)piperidine-3-carbonitrile (CAS 1087798-44-4)
- 2-Amino-N-(2,3,4-trifluorophenyl)acetamide (CAS 900640-59-7)
- 2-(Isopropylamino)-2-oxoacetic Acid (CAS 29262-57-5)
- 1,3-Dimethyl-5-(3-methyl-1h-pyrazol-1-yl)-1h-pyrazole-4-carboxylic acid (CAS 1251301-46-8)
- Gly-Neuroendocrine Regulatory Peptide-3 (human, mouse, rat) trifluoroacetate salt (CAS 1815618-19-9)
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