4-Fluoro-3-(2-hydroxypyrimidin-5-yl)benzonitrile CAS 1111113-52-0
| CAS No. | 1111113-52-0 |
| Molecular Formula | C11H6FN3O |
| Molecular Weight | 215.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 4-Fluoro-3-(2-hydroxypyrimidin-5-yl)benzonitrile (CAS 1111113-52-0), a certified reference material (molecular formula C11H6FN3O, MW 215.18 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 4-Fluoro-3-(2-hydroxypyrimidin-5-yl)benzonitrile is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 215.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H6FN3O |
| Molecular Weight | 215.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Fluoro Standards
- 4-Fluoro-1-(2-methoxyethoxy)-2-nitrobenzene (CAS 1092496-30-4)
- 2-(2-Fluoro-6-nitrophenyl)propane-1,3-diol (CAS 1131605-32-7)
- 1-Fluoro-2-(2-methoxyethoxy)-3-nitrobenzene (CAS 1233952-90-3)
- 2-Fluoro-3-(2-hydroxypyrimidin-5-yl)benzonitrile (CAS 1261965-61-0)
- 1-Fluoro-3-(2-methoxyethoxy)-2-nitrobenzene (CAS 131055-85-1)
- 1-fluoro-4-(2-methoxyethoxy)-2-nitrobenzene (CAS 1416626-24-8)
- 2-Fluoro-1-(2-methoxyethoxy)-4-nitrobenzene (CAS 221198-59-0)
- Methyl 5-fluoro-2,6-dimethoxynicotinate (CAS 2197053-22-6)
Recommended Standards
- (2S)-2-Amino-3-(2-Fluoro-3,4-Dihydroxyphenyl)Propanoic Acid (CAS 107597-46-6)
- 5,7-Dimethyl-2-(trifluoromethyl)-3H-imidazo[4,5-b]pyridine (CAS 1197880-04-8)
- 1-Ethoxy-2-fluoro-3-methoxy-4-nitrobenzene (CAS 1072945-58-4)
- 2-Amino-3-(2-fluoro-4,5-dimethoxyphenyl)propanoic acid (CAS 102034-49-1)
- 8-Piperazin-1-yl-2h-[1,2,4]triazolo[4,3-a]pyrazin-3-one (CAS 1544881-78-8)
- 2-Methyl-4-(4-methylphenyl)-1,3-thiazole-5-carboxylic acid (CAS 1007873-56-4)
- 4-(Difluoromethyl)-3-methyl-5-nitropyridine-2-sulfonamide (CAS 1807000-39-0)
- n-(2-Phenyl-2h-1,2,3-triazol-4-yl)methanesulfonamide (CAS 1250430-95-5)
- (R)-tert-Butyl 2-amino-2-(4-hydroxyphenyl)acetate (CAS 501692-32-6)
- Eltrombopag Impurity 45 (CAS CATO-C4X-119845)
- Sodium (E)-4-ethoxy-4-oxobut-2-enoate (CAS 55141-86-1)
- 5-chloro-2-methyl-thiazolo[5,4-b]pyridine (CAS 109202-21-3)
- 2-(3-Aminopropyl)anthracene-9,10-dione (CAS 87155-41-7)
- Acetyl-Exenatide trifluoroacetate salt (CAS 305815-28-5)
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