5-(2-Methoxyphenyl)pyrimidin-2-ol CAS 1111113-65-5

Purity 97%+In StockPharmaceutical Standards
CAS No.1111113-65-5
Molecular FormulaC11H10N2O2
Molecular Weight202.21 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-(2-Methoxyphenyl)pyrimidin-2-ol CAS 1111113-65-5 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

5-(2-Methoxyphenyl)pyrimidin-2-ol (CAS 1111113-65-5), molecular formula C11H10N2O2 and molecular weight 202.21 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 5-(2-Methoxyphenyl)pyrimidin-2-ol (C11H10N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC11H10N2O2
Molecular Weight202.21 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Nitrogen Atoms2

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Why CATO?