Ketorolac Impurity 51 CAS 111122-84-0
| CAS No. | 111122-84-0 |
| Molecular Formula | C18H13NO2 |
| Molecular Weight | 275.30 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Ketorolac Impurity 51 (CAS 111122-84-0) is a certified pharmaceutical impurity reference standard with the molecular formula C18H13NO2 and a molecular weight of 275.30 g/mol.
Structurally, Ketorolac Impurity 51 (C18H13NO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 275.30 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Ketorolac Impurity 51 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H13NO2 |
| Molecular Weight | 275.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 1 |
Related Ketorolac Standards
- Ketorolac Impurity 52 (CAS 147088-89-9)
- Ketorolac Impurity 57 (CAS CATO-C4X-166957)
- Ketorolac Impurity 58 (CAS CATO-C4X-166958)
- Ketorolac Impurity 22 (CAS CATO-C4X-166922)
- Ketorolac Impurity 26 (CAS 111930-01-9)
- Ketorolac EP Impurity H (CAS 80965-09-9)
- Ketorolac EP Impurity J (CAS 108061-03-6)
- Ketorolac Impurity 25 (CAS CATO-C4X-166925)
Recommended Standards
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- Tenoxicam EP Impurity B (CAS 59804-25-0)
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- Terbutaline Impurity 33 (CAS 1428441-56-8)
- Glycerol Impurity 15 (CAS CATO-C4X-217115)
- Paliperidone Impurity 116 (CAS 1200448-51-6)
- N-(methoxymethyl)-1,1-diphenyl-N-((trimethylsilyl)methyl)methanamine (CAS 1170701-52-6)
- (E)-Methyl 4-(4-methylpiperazin-1-yl)but-2-enoate (CAS 1868868-85-2)
- 1-(4-Chlorobenzyl)cyclopropane-1-carboxylic acid (CAS 1621-37-0)
- Apixaban Impurity 1 (CAS 503614-92-4)
- 7-(2H-1,3-Benzodioxol-5-yl)-2-cyclohexyl-[1,2,4]triazolo[1,5-a]pyridine-8-carbonitrile (CAS 860650-47-1)
- [5-(1-ADamantyl)-2-methylphenyl]amine hydrochloride (CAS 59974-07-1)
- Semaglutide impurity 62 (CAS CATO-C4X-222662)
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