3-[3-(Trifluoromethyl)phenoxy]propanoic Acid CAS 111140-93-3
| CAS No. | 111140-93-3 |
| Molecular Formula | C10H9F3O3 |
| Molecular Weight | 234.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-[3-(Trifluoromethyl)phenoxy]propanoic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
3-[3-(Trifluoromethyl)phenoxy]propanoic Acid (CAS 111140-93-3), molecular formula C10H9F3O3 and molecular weight 234.17 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-[3-(Trifluoromethyl)phenoxy]propanoic Acid (C10H9F3O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H9F3O3 |
| Molecular Weight | 234.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
Related Trifluoromethyl Standards
- 1000566-45-9 2-(3-(TRIFLUOROMETHYL)-4-METHOXYPHENYL)ACETIC ACID 2-(4-METHOXY-3-(TRIFLUOROMETHYL)PHENYL)ACETIC ACID 4-Methoxy-3-(trifluoromethyl)phenylacetic acid AS06117 (CAS 1000566-45-9)
- 2-[2-(trifluoromethyl)phenoxy]propanoic acid (CAS 119411-77-7)
- 2-((3-(Trifluoromethyl)benzyl)oxy)acetic acid (CAS 868277-48-9)
- 2-((4-(Trifluoromethyl)benzyl)oxy)acetic acid (CAS 602262-41-9)
- 2-(3-(Trifluoromethyl)phenoxy)propanoic acid (CAS 836-35-1)
- 2-(4-(Trifluoromethyl)phenoxy)propanoicacid (CAS 69484-34-0)
- 3-(2-(Trifluoromethyl)phenoxy)propanoic acid (CAS 926219-09-2)
- 3-[4-(Trifluoromethyl)phenoxy]propanoic acid (CAS 537013-50-6)
Recommended Standards
- 2-(2,3-Dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl)-2-oxoacetic acid (CAS 1094294-14-0)
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- Methyl 2-methoxy-6-(trifluoromethyl)benzoate (CAS 109296-87-9)
- Methyl 3-(2,2,2-trifluoro-1-hydroxyethyl)benzoate (CAS 1188323-28-5)
- N-(4-(3-Nitrophenyl)thiazol-2-yl)-4-phenoxybenzamide (CAS 313404-06-7)
- Tris(2,2′-bipyridyl-d8)ruthenium(II) hexafluorophosphate (CAS 67573-02-8)
- Blue Tetrazolium (CAS 1871-22-3)
- 1-(2H-1,3-benzodioxol-5-yl)cycloheptane-1-carbonitrile (CAS 1146290-24-5)
- 1,3-Dimethyl-5-(propylamino)-1h-pyrazole-4-carbonitrile (CAS 1341380-29-7)
- 1-(4-Fluorophenyl)-2-(methylthio)ethan-1-one (CAS 122831-40-7)
- 2-(Aminomethyl)-4-(difluoromethyl)-6-(trifluoromethoxy)pyridine-3-acetic acid (CAS 1806758-43-9)
- 4-Nitrobenzyl 4-(1H-indol-3-yl)butanoate (CAS 860784-02-7)
- Ethyl 3-Oxo-3-(2-tetrahydrofuryl)propanoate (CAS 887411-85-0)
- Neuropeptide Y (2-36), amide, porcine (CAS 102961-52-4)
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