(1-(tert-Butoxycarbonyl)-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)boronic acid CAS 1111638-14-2
| CAS No. | 1111638-14-2 |
| Molecular Formula | C12H17BN2O4 |
| Molecular Weight | 264.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(1-(tert-Butoxycarbonyl)-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)boronic acid (CAS 1111638-14-2) is a high-purity analytical reference standard with the molecular formula C12H17BN2O4 and a molecular weight of 264.09 g/mol.
The molecular framework of (1-(tert-Butoxycarbonyl)-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)boronic acid (C12H17BN2O4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H17BN2O4 |
| Molecular Weight | 264.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 2 |
Related tert Standards
- 5-(Tert-butoxycarbonyl)-[1,2,4]triazolo[1,5-a]pyrimidine-7-carboxylic acid (CAS 916212-31-2)
- 1-(tert-Butoxycarbonyl)-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid (CAS 1341037-48-6)
- 1-(tert-Butoxycarbonyl)-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-4-carboxylic acid (CAS 1781907-25-2)
- 1-(Tert-butoxycarbonyl)-2,3-dihydro-1H-pyrrolo[3,2-c]pyridine-2-carboxylic acid (CAS 2306260-70-6)
- 2-(Tert-butoxycarbonyl)-2,3-dihydro-1H-pyrrolo[3,4-c]pyridine-6-carboxylic acid (CAS 752202-61-2)
- 6-(Tert-butoxycarbonyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine-2-carboxylic acid (CAS 2090417-89-1)
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Recommended Standards
- Ethyl 2-(3-bromo-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)propanoate (CAS 2702997-65-5)
- 2-Amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinic acid (CAS 1239060-03-7)
- 8-Bromo-5H-[1,2,4]triazino[5,6-b]indol-3-amine (CAS 910443-21-9)
- 4-Methyl-5-nitro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1264292-75-2)
- 1-(Pyrimidin-2-yl)piperidine-3-carboxylic acid hydrochloride (CAS 1185296-02-9)
- Di(9,9'-spirobi[fluoren]-2-yl)(phenyl)phosphine oxide (CAS 824426-27-9)
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- 1-(Benzyloxy)-5-bromo-4-chloro-2-nitrobenzene (CAS 1403483-74-8)
- 2-Amino-4-methoxybenzylchloride (CAS 1261610-35-8)
- 2-Bromo-6-(trifluoromethyl)benzene-1-sulfonyl chloride (CAS 1431291-88-1)
- 1,5-Dimethyl-1H-benzo[d]imidazol-2(3H)-one (CAS 39513-28-5)
- Sarecycline (CAS 1035654-66-0)
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- Semaglutide impurity 81 (CAS CATO-C4X-222681)
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