6-Chloro-2-phenylpyridin-3-amine CAS 111185-30-9
| CAS No. | 111185-30-9 |
| Molecular Formula | C11H9ClN2 |
| Molecular Weight | 204.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 204.66 g/mol gives 6-Chloro-2-phenylpyridin-3-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
6-Chloro-2-phenylpyridin-3-amine (CAS 111185-30-9), molecular formula C11H9ClN2 and molecular weight 204.66 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-Chloro-2-phenylpyridin-3-amine (C11H9ClN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-Chloro-2-phenylpyridin-3-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H9ClN2 |
| Molecular Weight | 204.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 3-Chloro-4-(pyridin-2-yl)aniline (CAS 1044209-44-0)
- 4-Chloro-N-phenylpyridin-2-amine (CAS 1088907-66-7)
- 6'-Chloro-5-methyl-2,3'-bipyridine (CAS 1187168-72-4)
- 6-Chloro-4-phenyl-pyridin-2-ylamine (CAS 1211525-26-6)
- 5-Chloro-2-phenylpyridin-3-amine (CAS 1214337-63-9)
- 2-Chloro-6-methyl-3,3'-bipyridine (CAS 1214338-00-7)
- 2-Chloro-4-methyl-3,4'-bipyridine (CAS 1214343-79-9)
- 6-Chloro-5-methyl-3,4'-bipyridine (CAS 1214356-30-5)
Recommended Standards
- 6-(2-Chlorophenyl)pyridin-3-amine (CAS 1119089-76-7)
- 4-Chlorodiphenyl Ether (CAS 7005-72-3)
- Paliperidone Impurity 93 (CAS CATO-C4X-172493)
- Ornidazole Impurity 102 (CAS CATO-C4X-1331102)
- (3-(2-Nitrophenoxy)phenyl)boronic acid (CAS 1072945-95-9)
- 4-(4-Bromothiazol-2-yl)-N,N-dimethylaniline (CAS 1415564-69-0)
- 5-Methyl-2-(methylthio)-[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one (CAS 89853-03-2)
- 4-(5-Bromothiophen-2-yl)butanoic acid (CAS 89980-93-8)
- (4-(1-Methyl-1H-pyrazol-4-yl)phenyl)methanamine (CAS 1184589-25-0)
- 2-(6-Fluoro-1-methyl-1h-benzo[d]imidazol-2-yl)acetic acid, sodium salt (CAS 2490709-62-9)
- (S)-N1-Cyclopropyl-N1-((1-methylpyrrolidin-2-yl)methyl)ethane-1,2-diamine (CAS 1354018-87-3)
- 4-Ethylpyrimidin-2-amine (CAS 1193-85-7)
- 3-(5-Amino-4H-1,2,4-triazol-3-yl)benzonitrile (CAS 1016517-38-6)
- Semaglutide Impurity 4 (CAS CATO-C4X-22264)
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