{4-[(difluoromethyl)thio]phenyl}methanol CAS 1114822-77-3
| CAS No. | 1114822-77-3 |
| Molecular Formula | C8H8F2OS |
| Molecular Weight | 190.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
{4-[(difluoromethyl)thio]phenyl}methanol (C8H8F2OS) contains sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies {4-[(difluoromethyl)thio]phenyl}methanol (CAS 1114822-77-3), a certified reference material (molecular formula C8H8F2OS, MW 190.21 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), {4-[(difluoromethyl)thio]phenyl}methanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H8F2OS |
| Molecular Weight | 190.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related difluoromethyl Standards
- (2-((Difluoromethyl)thio)phenyl)methanol (CAS 261944-18-7)
- 2-((Difluoromethyl)thio)-4,6-dimethylpyrimidine (CAS 56228-50-3)
- 3-[(Difluoromethyl)thio]benzyl alcohol (CAS 261944-22-3)
- 4-(Difluoromethyl)bicyclo[2.2.1]heptane-1-carboxylic acid (CAS 1773511-56-0)
- 1-(Difluoromethyl)-3-(propoxymethyl)-1H-pyrazole (CAS 1855940-32-7)
- 2-(1-(Difluoromethyl)-3,5-dimethyl-1H-pyrazol-4-yl)ethan-1-ol (CAS 2098080-57-8)
- 2-(3-(Difluoromethyl)cyclohex-2-en-1-yl)acetic acid (CAS 2572387-74-5)
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Recommended Standards
- 2-Hydrazinyl-4-(1-methyl-1h-pyrazol-3-yl)pyrimidine (CAS 1006322-90-2)
- [3-(difluoromethoxy)phenyl]methanethiol (CAS 1208074-80-9)
- 2-(4-Fluoronaphthalen-1-yl)ethan-1-ol (CAS 1000521-40-3)
- Ethyl (1S,3R,4R)-3-fluoro-4-hydroxycyclohexane-1-carboxylate (CAS 1228360-09-5)
- 3-(1-Methyl-1H-imidazol-5-yl)prop-2-en-1-ol (CAS 363151-69-3)
- 5-[(carbamoylmethyl)sulfamoyl]-2-fluorobenzoic acid (CAS 926191-42-6)
- 2-Chloro-4-methoxy-6-nitroaniline (CAS 29105-95-1)
- Methyl 2-(4-chloropyrimidin-2-yl)acetate (CAS 66621-52-1)
- 1-(6-Methylpyrimidin-4-yl)-1H-pyrazole-4-carbaldehyde (CAS 1251120-50-9)
- 2-Ethynylquinoxaline (CAS 98813-70-8)
- 1-(2-Cyanophenyl)-N-isopropylmethanesulfonamide (CAS 31846-43-2)
- 3-(3-(2-Morpholinoethyl)-1H-1,2,4-triazol-5-yl)aniline (CAS 1279218-85-7)
- 2-(Pyridin-3-yl)-1,4a,5,12c-tetrahydro-2H,4H-benzo[5,6]chromeno[4,3-d][1,3]oxazine (CAS 251310-50-6)
- Tirzepatide Impurity 18 (CAS CATO-C4X-324018)
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