(3S)-1,3-Bis-O-(tert-Butyldimethylsilyl)-3-hydroxy-5,6-trans-vitamin D2 CAS 111594-58-2

Purity 97%+In StockPharmaceutical Standards
CAS No.111594-58-2
Molecular FormulaC40H72O2Si2
Molecular Weight641.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(3S)-1,3-Bis-O-(tert-Butyldimethylsilyl)-3-hydroxy-5,6-trans-vitamin D2 CAS 111594-58-2 chemical structure

Description

The molecular framework of (3S)-1,3-Bis-O-(tert-Butyldimethylsilyl)-3-hydroxy-5,6-trans-vitamin D2 (C40H72O2Si2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

(3S)-1,3-Bis-O-(tert-Butyldimethylsilyl)-3-hydroxy-5,6-trans-vitamin D2 (CAS 111594-58-2) is a high-purity analytical reference standard with the molecular formula C40H72O2Si2 and a molecular weight of 641.17 g/mol.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (3S)-1,3-Bis-O-(tert-Butyldimethylsilyl)-3-hydroxy-5,6-trans-vitamin D2 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC40H72O2Si2
Molecular Weight641.17 g/mol
Purity97%+
StorageStore at room temperature
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1988

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