Biotin Impurity C51 CAS 111822-45-8
| CAS No. | 111822-45-8 |
| Molecular Formula | C12H22N4O2S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Biotin Impurity C51 (CAS 111822-45-8), a pharmacopoeial impurity reference standard (molecular formula C12H22N4O2SHCl, MW 322.85 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, Biotin Impurity C51 is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 322.85 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C12H22N4O2S HCl |
| Molecular Weight | 322.85 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Biotin Standards
- Biotin-PEG4-amide-Alkyne (CAS 1006592-45-5)
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- Biotin-PEG2-C4-alkyne (CAS 1011268-28-2)
- Biotin-PEG2-C6-azide (CAS 1011268-29-3)
- Biotin EP Impurity F (CAS 101469-35-6)
- Biotin 4-amidobenzoic acid sodium salt (CAS 102418-74-6)
- Biotin-4-Fluorescein (CAS 1032732-74-3)
- Biotin Impurity 1((+)-Biotin (+)-Sulfoxide) (CAS 10406-89-0)
Recommended Standards
- CAS CATO-C4X-32408 (CAS CATO-C4X-32408)
- Rimegepant Impurity 79 HCl (CAS CATO-C4X-248779)
- Tetracaine Impurity 17 (CAS 1056627-94-1)
- Promethazine Teoclate (CAS 17693-51-5)
- 3-(2,4,5-Trimethylphenyl)pentan-3-ol (CAS 1443327-70-5)
- 3-(4-Methoxyphenyl)-1h-pyrazol-5-ol (CAS 124083-43-8)
- methyl 2-amino-5-(4-(tert-butyl)phenyl)thiazole-4-carboxylate (CAS 886361-34-8)
- Dibenzyl (1R,3S)-cyclohexane-1,3-diyldicarbamate (CAS 2177267-76-2)
- 5-Bromo-3-fluoro-2-(3-(trifluoromethyl)-3H-diazirin-3-yl)pyridine (CAS 2231673-45-1)
- Semaglutide impurity 64 (CAS CATO-C4X-222664)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com