5-(2,4-Dichloro-5-fluorophenyl)-1H-pyrazole-3-carboxylic acid CAS 1119299-75-0
| CAS No. | 1119299-75-0 |
| Molecular Formula | C10H5Cl2FN2O2 |
| Molecular Weight | 275.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-(2,4-Dichloro-5-fluorophenyl)-1H-pyrazole-3-carboxylic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 5-(2,4-Dichloro-5-fluorophenyl)-1H-pyrazole-3-carboxylic acid (CAS 1119299-75-0), a certified reference material (molecular formula C10H5Cl2FN2O2, MW 275.06 g/mol) for analytical method development and quality control.
5-(2,4-Dichloro-5-fluorophenyl)-1H-pyrazole-3-carboxylic acid (C10H5Cl2FN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-(2,4-Dichloro-5-fluorophenyl)-1H-pyrazole-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H5Cl2FN2O2 |
| Molecular Weight | 275.06 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichloro Standards
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Recommended Standards
- Methyl 4-amino-3-bromo-5-nitrobenzoate (CAS 105655-17-2)
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- N-(5-bromothiazol-2-yl)-2,2,2-trifluoroacetamide (CAS 745053-65-0)
- 1-Bromo-5-(trifluoromethyl)naphthalene (CAS 117539-59-0)
- 2-Phenoxynaphthalene-1,4-dione (CAS 220459-72-3)
- 1-(3-Methylthiophen-2-yl)butane-1,3-dione (CAS 1344204-72-3)
- (S)-3-Boc-5-methyl-1,2,3-oxathiazolidine 2,2-Dioxide (CAS 396074-50-3)
- Rimsulfuron Impurity 2 (CAS 151331-80-5)
- 1',3',3'-Trimethylspiro[chromene-2,2'-indolin]-6-ol (CAS 23001-29-8)
- N-(3-Chloro-4-fluorophenyl)tetrahydro-3-thiophenecarboxamide 1,1-Dioxide (CAS 923105-32-2)
- (3-((Diisopropylamino)methyl)-4-fluorophenyl)boronic acid (CAS 1704068-97-2)
- 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)-1H-pyrazole (CAS 1396750-11-0)
- 1-Benzyl-3-hydroxypiperidine-3-carboxylic acid hydrochloride (CAS 112197-87-2)
- Semaglutide Impurity 177 (CAS CATO-C4X-2226177)
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