Sitafloxacin impurity 90 CAS 112062-51-8
| CAS No. | 112062-51-8 |
| Molecular Formula | C11H8Cl2F2O3 |
| Molecular Weight | 297.08 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Sitafloxacin impurity 90 (CAS 112062-51-8) is a certified pharmaceutical impurity reference standard with the molecular formula C11H8Cl2F2O3 and a molecular weight of 297.08 g/mol.
Sitafloxacin impurity 90 (C11H8Cl2F2O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Sitafloxacin impurity 90 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H8Cl2F2O3 |
| Molecular Weight | 297.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
Related Sitafloxacin Standards
- R-Sitafloxacin Impurity 47 (CAS 1432056-70-6)
- S-Sitafloxacin Impurity 48 (CAS 144282-37-1)
- Sitafloxacin Impurity 30 (CAS CATO-C4X-115530)
- Sitafloxacin Impurity 17 (CAS 127199-00-2)
- Sitafloxacin Impurity 21 (CAS 182075-96-3)
- Sitafloxacin impurity 55 (CAS CATO-C4X-115555)
- Sitafloxacin Impurity 22 (CAS 101987-86-4)
- Sitafloxacin impurity 54 (CAS CATO-C4X-115554)
Recommended Standards
- 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)benzonitrile (CAS 479411-95-5)
- 3-iodo-4-nitro-1H-pyrrolo[2,3-b]pyridine (CAS 1000340-40-8)
- 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)benzonitrile (CAS 863868-28-4)
- 5,7-Dichloro-1,3-dihydroxy-9h-xanthen-9-one (CAS 1092332-61-0)
- Niraparib Impurity 40 (CAS CATO-C4X-232940)
- Docetaxel Impurity 61 (CAS CATO-C4X-161961)
- Rocuronium Impurity 15 (CAS 10429-07-9)
- 2-(Cyclopentylmethoxy)aniline (CAS 640767-46-0)
- 4-((2,5-Dioxopyrrolidin-1-yl)oxy)-4-oxobutanoic acid (CAS 102696-21-9)
- Semaglutide impurity 99 (CAS CATO-C4X-222699)
- 2-Oxo-1,2,3,4-tetrahydroquinoline-8-carbonitrile (CAS 1499556-74-9)
- 2-chloro-1-(5-hydroxy-1H-indol-3-yl)ethan-1-one (CAS 1531588-03-0)
- METHYL 1-(2-CHLOROPHENYL)-5-(5-(3-(METHYLSULFONYL)PHENYL)-1,3,4-THIADIAZOL-2-YL)-1H-PYRAZOLE-3-CARBOXYLATE (CAS 1454288-71-1)
- D-Lys16-Tirzepatide (CAS CATO-CPTD788918)
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