Penbutolol EP Impurity A CAS 112160-87-9
| CAS No. | 112160-87-9 |
| Molecular Formula | C18H29NO2 |
| Molecular Weight | 291.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Penbutolol EP Impurity A (C18H29NO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Penbutolol EP Impurity A (CAS 112160-87-9) is a certified pharmaceutical impurity reference standard with the molecular formula C18H29NO2 and a molecular weight of 291.43 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Penbutolol EP Impurity A meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H29NO2 |
| Molecular Weight | 291.43 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 1 |
Related Penbutolol Standards
Recommended Standards
- [2-(Hexyloxy)phenyl]-N-(tetrahydro-2-furanylmethyl)methanamine (CAS 1040692-60-1)
- Methyl 2-cyano-3-cyclohexyl-2-(cyclohexylmethyl)propanoate (CAS 1202778-92-4)
- N-{2-[4-(tert-Butyl)phenoxy]propyl}-N-(tetrahydro-2-furanylmethyl)amine (CAS 1040680-46-3)
- tert-Butyl 2-methyl-3-[(4-phenylbutan-2-yl)amino]propanoate (CAS 1221341-92-9)
- Dextromethorphan Impurity 30 (CAS 367520-36-3)
- Dronedarone Impurity 60 (CAS 1250316-60-9)
- Flurbiprofen Impurity 72 (CAS CATO-C4X-144472)
- Aceclofenac Impurity 20 (CAS CATO-C4X-153120)
- 2,3-Dibromo-6-fluorophenylacetic acid (CAS 1803716-62-2)
- 3-(Pentafluorosulfur)benzoyl chloride (CAS 401892-81-7)
- Linaclotide acetate (CAS 851199-59-2(free base))
- 2-(Methoxymethyl)oxirane (CAS 930-37-0)
- 1,2,3,4-Tetrahydroquinoline-7-carbonitrile (CAS 939758-76-6)
- Semaglutide Impurity 18 (CAS 1671100-14-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com