5-Chloro-1-methyl-1H-indole CAS 112398-75-1
| CAS No. | 112398-75-1 |
| Molecular Formula | C9H8ClN |
| Molecular Weight | 165.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Chloro-1-methyl-1H-indole (C9H8ClN) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 5-Chloro-1-methyl-1H-indole (CAS 112398-75-1), a certified reference material (molecular formula C9H8ClN, MW 165.62 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H8ClN |
| Molecular Weight | 165.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 2-Methyl-5-chloroindole (CAS 1075-35-0)
- 1-(3-Chlorophenyl)ethyl isocyanide (CAS 1041635-04-4)
- 2-(Chloromethyl)-1H-indole (CAS 121384-27-8)
- 91742-47-1 4-Fluoro(carbonyl-~13~C)benzoyl chloride DTXSID90583498 (CAS 91742-47-1)
- 1-(4-Chloro-1,2,5-thiadiazol-3-yl)pyrrolidin-3-ol (CAS 1343502-66-8)
- 5,5-Dimethyl-4,5,6,7-tetrahydro-2-benzothiophene-1-carboxylic acid (CAS 910635-40-4)
- (3,3-Difluoroazetidin-2-yl)methanol hydrochloride (CAS 2845280-88-6)
- 4-Methoxy-d3-benzaldehyde (CAS 342611-04-5)
- 4-Isopropyl-3-propyl-1H-1,2,4-triazol-5(4H)-one (CAS 135301-59-6)
- O-1821 (CAS 35482-50-9)
- 4'-Fluoro-[1,1'-biphenyl]-2-carbonitrile (CAS 89346-55-4)
- Erlotinib Impurity 103 (CAS 299912-61-1)
- 7-Methylpyrrolo[1,2-a]quinoxalin-4(5H)-one (CAS 159548-95-5)
- Peptide Impurity (CAS CATO-CPTD788810)
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