4-Chloro-3-(p-tolyl)isoxazolo[5,4-d]pyrimidine CAS 112467-60-4
| CAS No. | 112467-60-4 |
| Molecular Formula | C12H8ClN3O |
| Molecular Weight | 245.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-Chloro-3-(p-tolyl)isoxazolo[5,4-d]pyrimidine (CAS 112467-60-4), a certified reference material (molecular formula C12H8ClN3O, MW 245.66 g/mol) for analytical method development and quality control.
The molecular framework of 4-Chloro-3-(p-tolyl)isoxazolo[5,4-d]pyrimidine (C12H8ClN3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Chloro-3-(p-tolyl)isoxazolo[5,4-d]pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H8ClN3O |
| Molecular Weight | 245.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 7-chloro-2-(2-methylphenyl)[1,3]oxazolo[5,4-d]pyrimidine (CAS 1018053-24-1)
- 6-Chloro-4-(difluoromethyl)-2-isopropyl-2h-pyrazolo[3,4-b]pyridine (CAS 1018127-78-0)
- 6-Chloro-2-(2,2-difluoroethyl)-3,4-dimethyl-2H-pyrazolo[3,4-b]pyridine (CAS 1018127-86-0)
- 6-Chloro-4-(difluoromethyl)-2-propyl-2h-pyrazolo[3,4-b]pyridine (CAS 1018128-29-4)
- 7-Chloro-2-(p-tolyl)oxazolo[5,4-d]pyrimidine (CAS 1018142-92-1)
- 6-Chloro-4-(difluoromethyl)-2-ethyl-3-methyl-2H-pyrazolo[3,4-b]pyridine (CAS 1018165-01-9)
- 2-Chloro-N-((1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)methyl)acetamide (CAS 1172696-99-9)
- 2-Chloro-6-fluorobenzothiazole-4-carboxylic Acid Methyl Ester (CAS 1190321-72-2)
Recommended Standards
- 3-Amino-1-(5-chloro-2,4-dimethoxyphenyl)urea (CAS 1094655-20-5)
- 2-fluoro-4-nitrobenzene-1-sulfonyl chloride (CAS 1146290-36-9)
- 7-(4-Chlorophenyl)imidazo[1,2-a]pyrimidin-5(1H)-one (CAS 106263-56-3)
- 3-Amino-1-(4-chloro-2,5-dimethoxyphenyl)urea (CAS 1152851-50-7)
- tert-Butyl 4-((2S,3S)-2-amino-3-hydroxybutyl)piperazine-1-carboxylate (CAS 2427483-03-0)
- N-(3-(2-methylthiazol-4-yl)phenyl)acetamide (CAS 312925-73-8)
- Methyl 2-amino-3-morpholinopropanoate (CAS 1249655-04-6)
- 1-(3-(Hydroxymethyl)pyrrolidin-1-yl)-2-methylpropan-1-one (CAS 1247413-03-1)
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